AEG 3482

AEG 3482 Structure
AEG 3482 structure
Common Name AEG 3482
CAS Number 63735-71-7 Molecular Weight 280.326
Density 1.8±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H8N4O2S2 Melting Point N/A
MSDS N/A Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

Nat. Commun. 6 , 8746, (2015)

Metastatic tumour recurrence due to failed treatments remains a major challenge of breast cancer clinical management. Here we report that interleukin-1 receptor-associated kinase 1 (IRAK1) is overexpressed in a subset of breast cancers, in particular triple-n...

The Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastoma.

Springerplus 4 , 19, (2015)

Medulloblastoma (MB) comprises four molecularly and genetically distinct subgroups of embryonal brain tumors that develop in the cerebellum. MB mostly affects infants and children and is difficult to treat because of frequent dissemination of tumor cells with...