Quinine Hydrochloride Dihydrate
Quinine Hydrochloride Dihydrate structure
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Common Name | Quinine Hydrochloride Dihydrate | ||
|---|---|---|---|---|
| CAS Number | 6119-47-7 | Molecular Weight | 396.908 | |
| Density | N/A | Boiling Point | 633ºC at 760 mmHg | |
| Molecular Formula | C20H29ClN2O4 | Melting Point | 115-116 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 122 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A.
J. Pharm. Biomed. Anal. 30(4) , 1287-96, (2002) NAMI-A is a novel ruthenium complex with selective activity against metastases currently in Phase I clinical trials in The Netherlands. The photostability of this new agent in solid state and in solution has been investigated utilizing a stability-indicating ... |
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Quinine blocks a calcium-activated potassium conductance in mammalian enteric neurones.
Br. J. Pharmacol. 83(1) , 3-5, (1984) Quinine (100 microM) abolished the slow calcium-dependent afterhyperpolarization which occurs after an action potential in some neurones of the guinea-pig myenteric and submucous plexus. This occurred without any effect on the amplitude or time course of the ... |
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Treatment of severe malaria.
J. R. Soc. Med. 82 Suppl 17 , 44-50; discussion 50-1, (1989) In the treatment of severe Plasmodium falciparum infection antimalarial drugs should, ideally, be given by controlled rate intravenous infusion until the patient is able to swallow tablets. In cases where infection has been acquired in a chloroquine resistant... |
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In situ UV resonance Raman micro-spectroscopic localization of the antimalarial quinine in cinchona bark.
J. Phys. Chem. B 111(16) , 4171-7, (2007) Deep UV resonance Raman micro-spectroscopy (lambda(exc) = 244 nm) was applied for a highly sensitive, selective, and gentle localization of the antimalarial quinine in situ in cinchona bark. The high potential of the method was demonstrated by the detection o... |
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Delay discounting of oral morphine and sweetened juice rewards in dependent and non-dependent rats.
Psychopharmacol. Ser. 231(13) , 2633-45, (2014) Opioid-dependent humans are reported to show accelerated delay discounting of opioid rewards when compared to monetary rewards. It has been suggested that this may reflect a difference in discounting of consumable and non-consumable goods not specific to depe... |
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A Microfluidic Platform for the Rapid Determination of Distribution Coefficients by Gravity-Assisted Droplet-Based Liquid-Liquid Extraction.
Anal. Chem. 87 , 6265-70, (2015) The determination of pharmacokinetic properties of drugs, such as the distribution coefficient (D) is a crucial measurement in pharmaceutical research. Surprisingly, the conventional (gold standard) technique used for D measurements, the shake-flask method, i... |
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Is alkylation the main mechanism of action of the antimalarial drug artemisinin?. Robert A and Meunier B
Chem. Soc. Rev. , 273-274, (1998)
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