AP-18

AP-18 Structure
AP-18 structure
Common Name AP-18
CAS Number 55224-94-7 Molecular Weight 209.672
Density 1.1±0.1 g/cm3 Boiling Point 348.4±34.0 °C at 760 mmHg
Molecular Formula C11H12ClNO Melting Point N/A
MSDS Chinese USA Flash Point 164.5±25.7 °C
Symbol GHS07
GHS07
Signal Word Warning

TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide.

PLoS ONE 7(10) , e46917, (2012)

Hydrogen sulfide (H(2)S), which is produced endogenously from L-cysteine, is an irritant with pro-nociceptive actions. We have used measurements of intracellular calcium concentration, electrophysiology and behavioral measurements to show that the somatic pro...

TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice.

PLoS ONE 4 , e7596, (2009)

Nitric oxide (NO) can induce acute pain in humans and plays an important role in pain sensitization caused by inflammation and injury in animal models. There is evidence that NO acts both in the central nervous system via a cyclic GMP pathway and in the perip...

A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis.

Arthritis Rheum. 63 , 819-29, (2011)

To investigate the involvement of transient receptor potential ankyrin 1 (TRPA1) in inflammatory hyperalgesia mediated by tumor necrosis factor α(TNFα) and joint inflammation.Mechanical hyperalgesia was assessed in CD1 mice, mice lacking functional TRP vanill...

Characterization of a novel murine preadipocyte line, AP-18, isolated from subcutaneous tissue: analysis of adipocyte-related gene expressions.

Cell Biol. Int. 34 , 293-9, (2010)

Adipocyte lines are a useful tool for adipocyte research. Recently, a new preadipocyte line designated AP-18 was established from subcutaneous tissue of the C3H/He mouse. In this study, we further characterized AP-18 cells. Adipocyte differentiation was asses...

Torulaspora indica a novel yeast species isolated from coal mine soils.

Antonie van Leeuwenhoek 101(4) , 733-42, (2011)

Four yeast strains (APSS 805, APSS 806, APSS 815 and AP-18) belonging to a novel Torulaspora species were isolated from coal mine soils of Singareni in Andhra Pradesh state, India. Another strain (PBA-22) was isolated from agricultural field soil from Gujarat...