N,N'-Disuccinimidyl carbonate
N,N'-Disuccinimidyl carbonate structure
|
Common Name | N,N'-Disuccinimidyl carbonate | ||
|---|---|---|---|---|
| CAS Number | 74124-79-1 | Molecular Weight | 256.169 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 383.7±25.0 °C at 760 mmHg | |
| Molecular Formula | C9H8N2O7 | Melting Point | 190 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 185.9±23.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Pharmacological inhibition of MIF interferes with trophoblast cell migration and invasiveness.
Placenta 36(2) , 150-9, (2015) Macrophage migration inhibitory factor (MIF) is expressed by villous and extravillous cytotrophoblast. This study was aimed to investigate functional relevance of MIF for human trophoblast.MIF mRNA and protein were documented in cytotrophoblast (CT) and extra... |
|
|
Glassy-state stabilization of a dominant negative inhibitor anthrax vaccine containing aluminum hydroxide and glycopyranoside lipid A adjuvants.
J. Pharm. Sci. 104(2) , 627-39, (2015) During transport and storage, vaccines may be exposed to temperatures outside of the range recommended for storage, potentially causing efficacy losses. To better understand and prevent such losses, dominant negative inhibitor (DNI), a recombinant protein ant... |
|
|
Curdlan-Conjugated PLGA Nanoparticles Possess Macrophage Stimulant Activity and Drug Delivery Capabilities.
Pharm. Res. 32 , 2713-26, (2015) There is significant interest in the application of nanoparticles to deliver immunostimulatory signals to cells. We hypothesized that curdlan (immune stimulating polymer) could be conjugated to PLGA and nanoparticles from this copolymer would possess immunost... |
|
|
Novel Curcumin Diclofenac Conjugate Enhanced Curcumin Bioavailability and Efficacy in Streptococcal Cell Wall-induced Arthritis.
Indian J. Pharm. Sci. 76(5) , 415-22, (2014) Curcumin-diclofenac conjugate as been synthesized by esterification of phenolic group of curcumin with the acid moiety of diclofenac, and characterized by mass spectrometry, NMR, FTIR, DSC, thermogravimetric analysis and X-ray diffraction analysis. The relati... |
|
|
Codelivery of sorafenib and curcumin by directed self-assembled nanoparticles enhances therapeutic effect on hepatocellular carcinoma.
Mol. Pharm. 12(3) , 922-31, (2015) Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related mortality worldwide. Herein, we first reported the codelivery of sorafenib and curcumin by directed self-assembled nanoparticles (SCN) to enhance the therapeutic effect on HCC. ... |
|
|
Dissolution enhancement and in vitro performance of clarithromycin nanocrystals produced by precipitation-lyophilization-homogenization method.
Eur. J. Pharm. Biopharm. 88(3) , 886-96, (2014) The gastroduodenal diseases caused by Helicobacter pylori were commonly treated with antibiotic clarithromycin as a standard regimen. According to the poorly water-soluble of clarithromycin, the nanocrystal formulation was prepared. The aim of this study was ... |
|
|
Specific photothermal therapy to the tumors with high EphB4 receptor expression.
Biomaterials 68 , 32-41, (2015) Photothermal therapy (PTT) employs photo-absorbing agents to generate heat from optical energy, leading to the 'burning' of tumor cells. Real-time imaging of in vivo distribution of photothermal agents and monitoring of post-treatment therapeutic outcomes are... |
|
|
Stabilization of amorphous paracetamol based systems using traditional and novel strategies.
Int. J. Pharm. 477(1-2) , 294-305, (2014) There is a special interest in having pharmaceutical active ingredients in the amorphous state due to their increased solubility and therefore, higher bioavailability. Nevertheless, not all of them present stable amorphous phases. In particular, paracetamol i... |
|
|
Structure-topology-property correlations of sodium phosphosilicate glasses.
J. Chem. Phys. 143 , 064510, (2015) In this work, we investigate the correlations among structure, topology, and properties in a series of sodium phosphosilicate glasses with [SiO2]/[SiO2 + P2O5] ranging from 0 to 1. The network structure is characterized by (29)Si and (31)P magic-angle spinnin... |
|
|
Development of novel electrospun nanofibrous scaffold from P. Ricini And A. Mylitta silk fibroin blend with improved surface and biological properties.
Mater. Sci. Eng. C. Mater. Biol. Appl. 48 , 521-32, (2015) Biomaterials that stimulate cell attachment and proliferation without any surface modification (e.g. RGD coating) provide potent and cost effective scaffold for regenerative medicine. This study assessed the physico-chemical properties and cell supportive pot... |