2-Methyl-1H-indole-3-carbaldehyde

2-Methyl-1H-indole-3-carbaldehyde Structure
2-Methyl-1H-indole-3-carbaldehyde structure
Common Name 2-Methyl-1H-indole-3-carbaldehyde
CAS Number 5416-80-8 Molecular Weight 159.185
Density 1.2±0.1 g/cm3 Boiling Point 344.3±22.0 °C at 760 mmHg
Molecular Formula C10H9NO Melting Point 200-201 °C(lit.)
MSDS Chinese USA Flash Point 169.9±29.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Synthesis and antifungal activity of novel streptochlorin analogues.

Eur. J. Med. Chem. 92 , 776-83, (2015)

Streptochlorin, first isolated as a new antibiotic in 1988 from the lipophilic extracts of the mycelium of a Streptomyces sp, is an indole natural products with a variety of biological activities. Based on the methods developed for the synthesis of pimprinine...

Functionalization of benzylic C(sp(3))-H bonds of heteroaryl aldehydes through N-heterocyclic carbene organocatalysis.

Angew. Chem. Int. Ed. Engl. 52(42) , 11134-7, (2013)

Aryl aldehyde activation: Oxidative activation of 2-methylindole-3-carboxaldehyde (I) through N-heterocyclic carbene (NHC) organocatalysis generates heterocyclic ortho-quinodimethane (II) as a key intermediate. This intermediate then undergoes formal [4+2] cy...

(2-Methyl-1-phenyl-sulfonyl-1H-indol-3-yl)methanol.

Acta Crystallogr. Sect. E Struct. Rep. Online 64(2) , o542-o542, (2008)

In the title compound, C(16)H(15)NO(3)S, the plane of the phenyl ring forms a dihedral angle of 80.37 (8)° with the indole ring system. The crystal packing is stabilized by weak O-H⋯O hydrogen bonds which link the mol-ecules into infinite chains along the a a...