Monensin sodium salt
Monensin sodium salt structure
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Common Name | Monensin sodium salt | ||
|---|---|---|---|---|
| CAS Number | 22373-78-0 | Molecular Weight | 692.85 | |
| Density | N/A | Boiling Point | 766.3ºC at 760 mmHg | |
| Molecular Formula | C36H61NaO11 | Melting Point | 267-269ºC | |
| MSDS | Chinese USA | Flash Point | 229.2ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Development of anti-E6 pegylated lipoplexes for mucosal application in the context of cervical preneoplastic lesions.
Int. J. Pharm. 483(1-2) , 268-77, (2015) Cervical cancer induced by human papillomavirus (HPV) is the fourth highest mortality causing cancer in women despite the use of prophylactic vaccines. E6 targeting represents an attractive strategy to treat this cancer. Indeed, oncoprotein E6 is produced by ... |
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In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383.
Pharm. Res. 32 , 3937-51, (2015) To assess accumulation and lysosomal sequestration of 9 drugs used in respiratory indications (plus imipramine as positive control) in the alveolar macrophage (AM) cell line NR8383.For all drugs, uptake at 5 μM was investigated at 37 and 4°C to delineate acti... |
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Interneuron- and GABA(A) receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells.
Nat. Commun. 6 , 7364, (2015) Inhibitory synaptic plasticity is important for shaping both neuronal excitability and network activity. Here we investigate the input and GABA(A) receptor subunit specificity of inhibitory synaptic plasticity by studying cerebellar interneuron-Purkinje cell ... |
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PHF11 expression and cellular distribution is regulated by the Toll-Like Receptor 3 Ligand Polyinosinic:Polycytidylic Acid in HaCaT keratinocytes.
BMC Immunol. 16 , 69, (2015) Inflammatory skin diseases such as atopic dermatitis and psoriasis represent a complex interaction between the skin and infiltrating immune cells, resulting in damage to the skin barrier and increased inflammation. Polymorphisms in PHF11 have been associated ... |
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Rapid method for the simultaneous determination of six ionophores in feed by liquid chromatography/mass spectrometry.
J. AOAC Int. 95(4) , 1016-22, (2012) A simple and highly sensitive LC/MS method was developed for the simultaneous determination of six ionophores--lasalocid, monensin, laidlomycin, maduramycin, salinomycin, and narasin--in feed. The procedure involved extraction of 1 g of feed with 4 mL of meth... |
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Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells.
PLoS ONE 9(5) , e96695, (2014) The active form of vitamin D3, 1,25(OH)2D3, has significant immunomodulatory properties and is an important determinant in the differentiation of CD4+ effector T cells. The biological actions of 1,25(OH)2D3 are mediated by the vitamin D receptor (VDR) and are... |
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A new approach to the analysis of nicarbazin and ionophores in eggs by HPLC/MS/MS.
J. AOAC Int. 94 , 428-35, (2011) An HPLC/MS/MS method has been developed and validated for the quantification and confirmation of nicarbazin and ionophores (lasalocid, monensin, salinomycin, and narasin) in eggs. Nicarbazin is determined in the negative electrospray mode with a basic mobile ... |
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Determination of narasin and monensin in bovine, swine, and chicken tissues by liquid chromatography with tandem mass spectrometry: first action 2011.24.
J. AOAC Int. 95(4) , 959-91, (2012) The single-laboratory validation (SLV) of an LC-MS/MS method for determination and confirmation of two ionophores, narasin and monensin, in animal tissues is described. The data demonstrated linearity of matrix-matched calibration curves using a weighted (1/x... |
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Determination of monensin in milk samples by front-surface long-wavelength fluoroimmunoassay using nile blue-doped silica nanoparticles as labels
Talanta 94 , 195-200, (2012) Highlights ► A long-wavelength luminescent immunoassay for monensin using nanoparticles as labels is described for the first time. ► The fluorophor nile blue is encapsulated into silica matrix to obtain the label. ► Front-surface fluorescence is used as the d... |
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Monensin potentiates lead chelation efficacy of MiADMSA in rat brain post chronic lead exposure.
Food Chem. Toxicol. 50(12) , 4449-60, (2012) The present study evaluates combination therapy with a chelating agent, MiADMSA and a Na(+) ionophore, monensin against sub-chronic lead toxicity in rats. Animals were exposed to 0.1% lead in drinking water for 16 weeks and then treated with either MiADMSA at... |