Talanta 2012-05-30

Determination of monensin in milk samples by front-surface long-wavelength fluoroimmunoassay using nile blue-doped silica nanoparticles as labels

Juan Godoy-Navajas, Maria Paz Aguilar-Caballos, Agustina Gómez-Hens, Juan Godoy-Navajas, Maria Paz Aguilar-Caballos, Agustina Gómez-Hens

Index: Talanta 94 , 195-200, (2012)

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Abstract

Highlights ► A long-wavelength luminescent immunoassay for monensin using nanoparticles as labels is described for the first time. ► The fluorophor nile blue is encapsulated into silica matrix to obtain the label. ► Front-surface fluorescence is used as the detection system. ► Monensin residues in milk can be directly monitored owing to the relatively low LOD of the method. ► The sample treatment consists in protein removal and further dilution.