3-((Methoxycarbonyl)amino)phenyl m-tolylcarbamate

3-((Methoxycarbonyl)amino)phenyl m-tolylcarbamate Structure
3-((Methoxycarbonyl)amino)phenyl m-tolylcarbamate structure
Common Name 3-((Methoxycarbonyl)amino)phenyl m-tolylcarbamate
CAS Number 13684-63-4 Molecular Weight 300.309
Density 1.2±0.1 g/cm3 Boiling Point 510.3±60.0 °C at 760 mmHg
Molecular Formula C16H16N2O4 Melting Point 140-144°C
MSDS Chinese USA Flash Point 262.4±32.9 °C
Symbol GHS09
GHS09
Signal Word Warning

Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors

Bioorg. Med. Chem. Lett. 19 , 6793-6, (2009)

The screening of known medicinal agents against new biological targets has been shown to be a valuable approach for revealing new pharmacology of marketed compounds. Recently, carbamate, urea and ketone inhibitors of fatty acid amide hydrolase (FAAH) have bee...

The influence of lipophilicity and formulation on the distribution of pesticides in laboratory-scale sediment/water systems.

Pest Manag. Sci. 59(2) , 238-44, (2003)

Pesticide reaching surface waters will be sorbed by sediment. This sorption process and the influence of pesticide formulation have been examined at 10 degrees C in small-scale systems having 2-cm depth of sediment and 8-cm overlying water stirred gently. Eig...

Purification and properties of an Arthrobacter oxydans P52 carbamate hydrolase specific for the herbicide phenmedipham and nucleotide sequence of the corresponding gene.

J. Bacteriol. 174(20) , 6600-7, (1992)

Arthrobacter oxydans P52 isolated from soil samples was found to degrade the phenylcarbamate herbicides phenmedipham and desmedipham cometabolically by hydrolyzing their central carbamate linkages. The phenylcarbamate hydrolase (phenmedipham hydrolase) respon...

Expression of a bacterial gene in transgenic plants confers resistance to the herbicide phenmedipham.

Plant Mol. Biol. 25(6) , 977-87, (1994)

Tobacco plants were genetically engineered to express a detoxifying pathway for the herbicide phenmedipham. A gene from Arthrobacter oxidans strain P52 that encodes an enzyme catalysing the hydrolytic cleavage of the carbamate compound phenmedipham has recent...

Effects of different soil types on the Collembolans Folsomia candida and Hypogastrura assimilis using the herbicide Phenmedipham.

Arch. Environ. Contam. Toxicol. 49(3) , 343-52, (2005)

Soil ecotoxicology studies are usually performed in standard soils such as Organization for Economic Cooperation and Development artificial soil or LUFA ST. 2.2, a natural soil. When assessing the toxic effects in the environment, soil properties are often di...

Ethoxylated rapeseed oil derivatives as novel adjuvants for herbicides.

Pest Manag. Sci. 58(12) , 1243-9, (2002)

Ethoxylates of rapeseed oil and of methylated rapeseed oil were synthesized and tested as adjuvants for 2,4-D and phenmedipham. Provided they had less than 6 units of ethylene oxide (EO), 1.0 to 10 g litre(-1) ethoxylates in water induced droplet spreading on...

Biological monitoring of phenmedipham: determination of m-toluidine in urine.

Arch. Toxicol. 75(3) , 145-9, (2001)

Phenmedipham [methyl-3-(3-methylphenylcarbamoyloxy)carbamate] is used as a herbicide, especially in the growing of sugar beet and strawberries. During metabolism of the substance in rats, the two carbamate moieties of phenmedipham are cleaved and the metaboli...

Acute and chronic toxicity of Betanal(®)Expert and its active ingredients on nontarget aquatic organisms from different trophic levels.

Environ. Toxicol. 27(9) , 537-48, (2012)

As a way to improve the efficacy to target organisms, new pesticide generation is based on technologically advanced coformulations of two or more active ingredients. One example is Betanal(®)Expert, a postemergence herbicide composed of an Advanced Micro Drop...

Liquid chromatographic/mass spectrometric determination of desmedipham and phenmedipham and their metabolites in soil.

J. AOAC Int. 84(5) , 1407-12, (2001)

A simple method is described for the simultaneous determination of residues of 2 carbamate herbicides (phenmedipham and desmedipham) and related metabolites (m-aminophenol, aniline, and m-toluidine) in soil. The analytes are extracted from spiked soils with m...

[Analysis of phenmedipham in agricultural products by HPLC].

Shokuhin Eiseigaku Zasshi 46(6) , 277-81, (2005)

An analytical method was developed for the determination of phenmedipham (PM) in agricultural products using reversed-phase high-performance liquid chromatography with UV detection. A sample was extracted with acetonitrile, and the acetonitrile layer was sepa...