prochloraz
prochloraz structure
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Common Name | prochloraz | ||
|---|---|---|---|---|
| CAS Number | 67747-09-5 | Molecular Weight | 376.665 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 499.8±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H16Cl3N3O2 | Melting Point | 46-49°C | |
| MSDS | Chinese USA | Flash Point | 256.1±31.5 °C | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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LC-MS analysis of the plasma metabolome--a novel sample preparation strategy.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 978-979 , 83-8, (2015) Blood plasma is a well-known body fluid often analyzed in studies on the effects of toxic compounds as physiological or chemical induced changes in the mammalian body are reflected in the plasma metabolome. Sample preparation prior to LC-MS based analysis of ... |
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Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola.
PLoS ONE 6(6) , e20973, (2011) A structural rationale for recent emergence of azole (imidazole and triazole) resistance associated with CYP51 mutations in the wheat pathogen Mycosphaerella graminicola is presented, attained by homology modelling of the wild type protein and 13 variant prot... |
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Human poisoning with prochloraz imidazole fungicide.
Clin. Toxicol. (Phila.) 51(10) , 1237-8, (2013)
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Ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry to identify contaminants in water: an insight on environmental forensics.
J. Chromatogr. A. 1345 , 86-97, (2014) Ultra-high pressure liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QqTOF-MS) acquiring full scan MS data for quantification, and automatic data dependent information product ion spectra (IDA-MS/MS) without any predefinition of the io... |
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Antiandrogenic mechanisms of pesticides in human LNCaP prostate and H295R adrenocortical carcinoma cells.
Toxicol. Sci. 143(1) , 126-35, (2014) Several pesticides suspected or known to have endocrine disrupting effects were screened for pro- or antiandrogenic properties by determining their effects on proliferation, prostatic-specific antigen (PSA) secretion and androgen receptor (AR) expression, and... |
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Toxic effects of pesticide mixtures at a molecular level: their relevance to human health.
Toxicology 307 , 136-45, (2013) Pesticides almost always occur in mixtures with other ones. The toxicological effects of low-dose pesticide mixtures on the human health are largely unknown, although there are growing concerns about their safety. The combined toxicological effects of two or ... |
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Persistent developmental toxicity in rat offspring after low dose exposure to a mixture of endocrine disrupting pesticides.
Reprod. Toxicol. 34(2) , 237-50, (2012) There is growing concern of permanent damage to the endocrine and nervous systems after developmental exposure to endocrine disrupting chemicals. In this study the permanent reproductive and neurobehavioral effects of combined exposure to five endocrine disru... |
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Combined exposure to endocrine disrupting pesticides impairs parturition, causes pup mortality and affects sexual differentiation in rats.
Int. J. Androl. 33(2) , 434-42, (2010) Risk assessment is currently based on the no observed adverse effect levels (NOAELs) for single compounds. Humans are exposed to a mixture of chemicals and recent studies in our laboratory have shown that combined exposure to endocrine disrupters can cause ad... |
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Species extrapolation for the 21st century.
Environ. Toxicol. Chem. 30(1) , 52-63, (2011) Safety factors are used in ecological risk assessments to extrapolate from the toxic responses of laboratory test species to all species representing that group in the environment. More accurate extrapolation of species responses is important. Advances in und... |
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Prochloraz-induced oocyte maturation in rainbow trout (Oncorhynchus mykiss), a molecular and functional analysis.
Toxicol. Sci. 118(1) , 61-70, (2010) In the present study, we aimed at characterizing the effect of prochloraz, an imidazole fungicide, on the oocyte meiotic maturation process in a freshwater teleost species, the rainbow trout (Oncorhynchus mykiss). Full-grown post-vitellogenic ovarian follicle... |