EGNHS
EGNHS structure
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Common Name | EGNHS | ||
|---|---|---|---|---|
| CAS Number | 70539-42-3 | Molecular Weight | 456.35800 | |
| Density | 1.52g/cm3 | Boiling Point | 603.4ºC at 760 mmHg | |
| Molecular Formula | C18H20N2O12 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 318.7ºC | |
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Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1.
Oncotarget 6 , 36338-53, (2015) The mitochondrial accumulation of ATF2 is involved in tumor suppressor activities via cytochrome c release in melanoma cells. However, the signaling pathways that connect mitochondrial ATF2 accumulation and cytochrome c release are not well documented.Several... |
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Functionally distinct patterns of nucleosome remodeling at enhancers in glucocorticoid-treated acute lymphoblastic leukemia.
Epigenetics Chromatin 8 , 53, (2015) Precise nucleosome positioning is an increasingly recognized feature of promoters and enhancers, reflecting complex contributions of DNA sequence, nucleosome positioning, histone modification and transcription factor binding to enhancer activity and regulatio... |
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Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B.
J. Biol. Chem. 290 , 28329-42, (2015) Transcription factor Runx2 controls bone development and osteoblast differentiation by regulating expression of a significant number of bone-related target genes. Here, we report that transcriptional activation and repression of the Runx2 gene via its osteobl... |
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Development of dual fluorescent stage specific reporter strain of Toxoplasma gondii to follow tachyzoite and bradyzoite development in vitro and in vivo.
Microbes Infect. 18 , 39-47, (2016) Toxoplasma gondii is a protozoan that infects 30% of humans as intermediate hosts. T Sexual reproduction can occur only within the intestinal tract of felines, however, infection in other mammals and birds is associated with asexual replication and interconve... |
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Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells.
Proc. Natl. Acad. Sci. U. S. A. 87(15) , 5978-82, (1990) Erythropoietin is known to be a hematopoietic growth factor with a singularly specific action on the proliferation and differentiation of erythroid progenitor cells. We have observed a dose-dependent proliferative action of human recombinant erythropoietin on... |
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Subunit structure of the nonactivated human estrogen receptor.
Proc. Natl. Acad. Sci. U. S. A. 92(6) , 2179-83, (1995) The nonactivated estrogen receptor of human MCF-7 mammary carcinoma cells was investigated with respect to stoichiometry of protein subunits. The native receptor complex stabilized by molybdate had a molecular mass of approximately 300 kDa. Chemical cross-lin... |
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ChIA-PET analysis of transcriptional chromatin interactions.
Methods 58(3) , 289-99, (2012) Long-range chromatin contacts between specific DNA regulatory elements play a pivotal role in gene expression regulation, and a global characterization of these interactions in the 3-dimensional (3D) chromatin structure is imperative in understanding signalin... |
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Subunit composition of the untransformed glucocorticoid receptor in the cytosol and in the cell.
Eur. J. Biochem. 204(1) , 75-84, (1992) We have used bifunctional reagents to examine the subunit composition of the non-DNA-binding form of the rat and human glucocorticoid receptor. Treatment of intact cells and cell extracts with a reversible cross-linker, followed by electrophoretic analysis of... |
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The Drosophila morphogenetic protein Bicoid binds DNA cooperatively.
Development 122(4) , 1195-206, (1996) The Drosophila morphogenetic protein Bicoid, encoded by the maternal gene bicoid, is required for the development of the anterior structures in the embryo. Bicoid, a transcriptional activator containing a homeodomain, is distributed in an anterior-to-posterio... |
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Modulation of two forms of tumor necrosis factor receptors and their cellular response by soluble receptors and their monoclonal antibodies.
J. Biol. Chem. 267(29) , 20892-9, (1992) Recently, two different receptors for human tumor necrosis factor (TNF) with molecular masses of 60 kDa (p60) and 80 kDa (p80) have been identified. In this report, we investigated the effect of the soluble forms of these receptors and monoclonal antibodies a... |