Name | 4-O-(2,5-dioxopyrrolidin-1-yl) 1-O-[2-[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutanoyl]oxyethyl] butanedioate |
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Synonyms |
EGS
MFCD00049057 Peg-SS EGBSS |
Description | EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
Alkyl/ether |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.52g/cm3 |
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Boiling Point | 603.4ºC at 760 mmHg |
Molecular Formula | C18H20N2O12 |
Molecular Weight | 456.35800 |
Flash Point | 318.7ºC |
Exact Mass | 456.10200 |
PSA | 179.96000 |
Index of Refraction | 1.56 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
RIDADR | NONH for all modes of transport |