EF24

EF24 Structure
EF24 structure
Common Name EF24
CAS Number 342808-40-6 Molecular Weight 347.78600
Density N/A Boiling Point N/A
Molecular Formula C19H16ClF2NO Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA.

Sci. Rep. 5 , 11836, (2015)

Cantharidin is an active constituent of mylabris, a traditional Chinese medicine, and is a potent and selective inhibitor of protein phosphatase 2A (PP2A) that plays an important role in cell cycle control, apoptosis, and cell-fate determination. In the prese...

Inflammatory stimuli promote growth and invasion of pancreatic cancer cells through NF-κB pathway dependent repression of PP2Ac.

Cell Cycle 15 , 381-93, (2016)

Previous studies have indicated that inflammatory stimulation represses protein phosphatase 2A (PP2A), a well-known tumor suppressor. However, whether PP2A repression participates in pancreatic cancer progression has not been verified. We used lipopolysacchar...

Induced expression and functional effects of aquaporin-1 in human leukocytes in sepsis.

Crit. Care 17 , R199, (2014)

Gene expression profiling was performed via DNA microarrays in leukocytes from critically ill trauma patients nonseptic upon admission to the ICU, who subsequently developed either sepsis (n = 2) or severe sepsis and acute respiratory distress syndrome (n = 3...