EF24
EF24 structure
|
Common Name | EF24 | ||
|---|---|---|---|---|
| CAS Number | 342808-40-6 | Molecular Weight | 347.78600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H16ClF2NO | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
Use of EF24EF24 is a curcumin analogue with greater anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK[1][2]. |
| Name | (3Z,5Z)-3,5-bis[(2-fluorophenyl)methylidene]piperidin-4-one,hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | EF24 is a curcumin analogue with greater anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK[1][2]. |
|---|---|
| Related Catalog | |
| References |
[2]. Mosley CA, et al. Highly active anticancer curcumin analogues. Adv Exp Med Biol. 2007;595:77-103. |
| Molecular Formula | C19H16ClF2NO |
|---|---|
| Molecular Weight | 347.78600 |
| Exact Mass | 347.08900 |
| PSA | 29.10000 |
| LogP | 4.73490 |
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H400 |
| Precautionary Statements | P273 |
| RIDADR | UN 3077 9 / PGIII |
![acetic acid,3,5-bis[(2-fluorophenyl)methylidene]piperidin-4-one structure](https://www.chemsrc.com/caspic/353/342808-41-7.png)
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| EF-24 |
| (3E,5E)-3,5-bis[(2-fluorophenyl)methylene]-4-piperidinone |