Amino methacrylate copolymer
Amino methacrylate copolymer structure
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Common Name | Amino methacrylate copolymer | ||
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| CAS Number | 24938-16-7 | Molecular Weight | 399.522 | |
| Density | N/A | Boiling Point | 187ºC at 760mmHg | |
| Molecular Formula | C21H37NO6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | >250℃ | |
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Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions.
Chem. Pharm. Bull. 60(11) , 1468-73, (2012) In this study, amorphous solid dispersions containing dutasteride and various excipients, manufactured by spray-drying processes, were characterized to determine the effects on their ability to form supersaturated solutions and to identify the effects of supe... |
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Effect of aminoalkyl methacrylate copolymer E/HCl on in vivo absorption of poorly water-soluble drug.
Drug Dev. Ind. Pharm. 39(11) , 1698-705, (2013) This study aimed to investigate in vivo absorption of tacrolimus formulated as a solid dispersion using Eudragit E®/HCl (E-SD). E-SD is an aminoalkyl methacrylate copolymer that can be dissolved under neutral pH conditions. E-SD was used alone as a solid disp... |
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Eudragit E as excipient for production of granules and tablets from Phyllanthus niruri L spray-dried extract.
AAPS PharmSciTech 8(2) , Article 34, (2007) The aim of this study was to investigate the feasibility of using Eudragit E as a granulating agent for a spray-dried extract from Phyllanthus niruri to obtain tablets containing a high dose of this product. The granules were developed by wet granulation and ... |
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Studies on gynaecological hydrophilic lactic acid preparations. Part 5: The use of Eudragit E-100 as lactic acid carrier in intravaginal tablets.
Pharmazie 58(4) , 260-2, (2003) Intravaginal tablets based on hydrophilic methylcellulose and containing lactic acid complexed with Eudragit E-100 undergo deformation under standard conditions. The high flow--limit of gel originating from the tablets as well as its dynamic viscosity should ... |
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Evaluation of in vitro dissolution and in vivo oral absorption of dutasteride-loaded eudragit E nanoparticles.
Drug Res. (Stuttg.) 63(6) , 326-30, (2013) The present study sought to evaluate the pharmacokinetics of dutasteride-loaded Eudragit E nanoparticle in rats. In addition, the study investigated the effect of increasing drug load on the in vitro solubility and dissolution behavior of dutasteride together... |
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In vitro evaluation of dissolution behavior for a colon-specific drug delivery system (CODES) in multi-pH media using United States Pharmacopeia apparatus II and III.
AAPS PharmSciTech 3(4) , E33, (2002) United States Pharmacopeia dissolution apparatus II (paddle) and III (reciprocating cylinder) coupled with automatic sampling devices and software were used to develop a testing procedure for acquiring release profiles of colon-specific drug delivery system (... |
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A cationic polymer, Eudragit-E, as a new liquid embolic material for arteriovenous malformations.
Neuroradiology 38 Suppl 1 , S151-6, (1996) We have developed a new liquid material for embolisation of arteriovenous malformations: a mixture of methyl and butyl methacrylate, plus dimethylaminoethyl methacrylate copolymer (Eudragit-E) in a solvent consisting of ethanol and iopamidol. Upon contact wit... |
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Characterisation of solid dispersions of paracetamol and EUDRAGIT E prepared by hot-melt extrusion using thermal, microthermal and spectroscopic analysis.
Int. J. Pharm. 354(1-2) , 158-67, (2008) Hot-melt extrusion has attracted considerable interest within the pharmaceutical industry. However, there remains some uncertainty as to how to characterise the physical structure of the extruded systems, particularly in terms of identifying the nature of the... |
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Nonadhesive liquid embolic agent: role of its components in histologic changes in embolized arteries.
Acad. Radiol. 5(3) , 198-206, (1998) The authors evaluated the safety and efficacy of a nonadhesive liquid embolic material and the role of its components in histologic changes in embolized arteries.A Eudragit-E mixture (Rohm Chemische Fabrik, Darmstadt, Germany) was made of a cationic copolymer... |
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Aminoalkyl methacrylate copolymers for improving the solubility of tacrolimus. I: Evaluation of solid dispersion formulations.
Int. J. Pharm. 428(1-2) , 18-24, (2012) The aim of this study was to investigate the effect of Eudragit E/HCl (E-SD) on the reprecipitation of a poorly water-soluble drug, tacrolimus. To evaluate the inhibition of reprecipitation of E-SD, reprecipitation studies on tacrolimus were conducted using a... |