(−)-N-Methylephedrine
(−)-N-Methylephedrine structure
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Common Name | (−)-N-Methylephedrine | ||
|---|---|---|---|---|
| CAS Number | 552-79-4 | Molecular Weight | 179.259 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 251.3±0.0 °C at 760 mmHg | |
| Molecular Formula | C11H17NO | Melting Point | 86-88 ℃(lit.) | |
| MSDS | Chinese USA | Flash Point | 96.9±20.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Wide-range screening of psychoactive substances by FIA-HRMS: identification strategies.
Anal. Bioanal. Chem 407 , 4567-80, (2015) Recreational drugs (illicit drugs, human and veterinary medicines, legal highs, etc.) often contain lacing agents and adulterants which are not related to the main active ingredient. Serious side effects and even the death of the consumer have been related to... |
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The relevance of the urinary concentration of ephedrines in anti-doping analysis: determination of pseudoephedrine, cathine, and ephedrine after administration of over-the-counter medicaments.
Ther. Drug Monit. 31(4) , 520-6, (2009) This article describes a method for the detection and quantitation of cathine, pseudoephedrine, ephedrine, and methylephedrine in urine, using their deuterated analogues as internal standards and derivatization to form the corresponding trimethylsilyl derivat... |
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Comparison of contents of five ephedrine alkaloids in three official origins of Ephedra Herb in China by high-performance liquid chromatography.
J. Nat. Med. 65(3-4) , 623-8, (2011) In the present paper, a fast and economical HPLC method [on a Phenomenex Polar-RP column with a solution of (phosphoric acid:triethylamine:dibutylamine:water = 0.40:0.1:0.2:499.3) and methanol] is developed, and applied for the determination of norephedrine, ... |
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Simultaneous quantification of six ephedrines in a Mahwang preparation and in urine by high-performance liquid chromatography.
Biomed. Chromatogr. 19(5) , 337-42, (2005) A rapid and reliable high-performance liquid chromatographic method was developed and validated for the simultaneous determination of norephedrine (NE), norpseudoephedrine (NPE), ephedrine (E), pseudoephedrine (PE), methylephedrine (ME) and methylpseudoephedr... |
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Results of stability studies with doping agents in urine.
J. Anal. Toxicol. 31(9) , 543-8, (2007) For a correct interpretation of analytical results in doping control, knowledge on the stability of prohibited substances in the urinary matrix is a prerequisite. So far, limited data is available on the stability of prohibited substances in unaltered urine b... |
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Fast stereoselective reactions in electrosprayed Co(II)/neurotransmitter nanodroplets.
Chem. Commun. (Camb.) (22) , 2544-6, (2008) Collision induced dissociation (CID) of the m/z 479 ion, formed by ESI of Co(NO3)2-CH3OH solutions with either pure (1S,2S)-(+)-N-methylpseudoephedrine or its mixtures with (1S,2R)-(+)- or (1R,2S)-(-)-ephedrine, provides compelling evidence for fast, stereose... |
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Simultaneous determination of methylephedrine and noscapine in human plasma by liquid chromatography-tandem mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 820(2) , 175-82, (2005) A selective and sensitive method has been developed and validated for simultaneous quantification of methylephedrine and noscapine in human plasma. Analytes were extracted from human plasma samples by liquid-liquid extraction, separated on a Diamonsil C18 col... |
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A prospective cohort study of pregnancy outcomes of women inadvertently exposed to methylephedrine in the 1st trimester of pregnancy.
J. Obstet. Gynaecol. 30(6) , 563-6, (2010) No information is currently available on the safety of methylephedrine, a component of various cold medications available in South Korea. With previous approval by an Institutional Review Board, 349 women inadvertently exposed to methylephedrine during the 1s... |
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Simultaneous determination of methylephedrine and pseudoephedrine in human urine by CE with electrochemiluminescence detection and its application to pharmacokeinetics.
Biomed. Chromatogr. 23(11) , 1138-44, (2009) A novel method for the determination of ephedra alkaloids (methylephedrine and pseudoephedrine) was developed by electrophoresis capillary (CE) separation and electrochemiluminesence detection (ECL). The use of ionic liquid (1-butyl-3-methylimidazolium tetraf... |
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Intoxication with over-the-counter antitussive medication containing dihydrocodeine and chlorpheniramine causes generalized convulsion and mixed acidosis.
Intern. Med. 47(11) , 1013-5, (2008) We report a 35-year-old man who was referred to our hospital with generalized convulsion and mixed acidosis presumably caused by abuse of SS-BRON tablets, an over-the-counter (OTC) antitussive medication sold in Japan. These tablets contain dihydrocodeine pho... |