(−)-N-Methylephedrine

Modify Date: 2024-01-02 12:21:04

(−)-N-Methylephedrine Structure
(−)-N-Methylephedrine structure
Common Name (−)-N-Methylephedrine
CAS Number 552-79-4 Molecular Weight 179.259
Density 1.0±0.1 g/cm3 Boiling Point 251.3±0.0 °C at 760 mmHg
Molecular Formula C11H17NO Melting Point 86-88 ℃(lit.)
MSDS Chinese USA Flash Point 96.9±20.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name Methylephedrine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 251.3±0.0 °C at 760 mmHg
Melting Point 86-88 ℃(lit.)
Molecular Formula C11H17NO
Molecular Weight 179.259
Flash Point 96.9±20.6 °C
Exact Mass 179.131012
PSA 23.47000
LogP 1.74
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.530
Storage condition Refrigerator (+4°C)

 MSDS

Name: (-)-N-Methylephedrine, 99% Material Safety Data Sheet
Synonym: (-)-alpha-[1-(Dimethylamino)ethyl]benzenemethanol; (-)-(1R,2S)-2-Dimethylamino-1-phenyl-1-propanol; Ephedrine, N-methyl-
CAS: 552-79-4
Section 1 - Chemical Product MSDS Name: (-)-N-Methylephedrine, 99% Material Safety Data Sheet
Synonym: (-)-alpha-[1-(Dimethylamino)ethyl]benzenemethanol; (-)-(1R,2S)-2-Dimethylamino-1-phenyl-1-propanol; Ephedrine, N-methyl-
SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
552-79-4 (-)-N-Methylephedrine 99 209-022-7
Hazard Symbols: XN
Risk Phrases: 22 36/37/38
SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful if swallowed. Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air).Light sensitive. Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May cause central nervous system stimulation.
Inhalation:
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May be harmful if inhaled.
Chronic:
No information found.
SECTION 4 - FIRST AID MEASURES
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Remove contaminated clothing and shoes.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
SECTION 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.
SECTION 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Store protected from light. Keep from contact with moist air and steam.
Storage:
Store in a tightly closed container. Keep refrigerated. (Store below 4C/39F.) Store protected from moisture. Store protected from light.
SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 552-79-4: Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Crystals
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 85-88 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Not available.
Specific Gravity/Density: Not available.
Molecular Formula: C11H17NO
Molecular Weight: 179.26
SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Sensitive to light.
Hygroscopic: absorbs moisture or water from the air.
Conditions to Avoid:
Incompatible materials, light, dust generation, exposure to moist air or water.
Incompatibilities with Other Materials:
Acid chlorides, acid anhydrides, acids, oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 552-79-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
(-)-N-Methylephedrine - Not listed by ACGIH, IARC, or NTP.
SECTION 12 - ECOLOGICAL INFORMATION
SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations.
SECTION 14 - TRANSPORT INFORMATION IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:


SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 552-79-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 552-79-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 552-79-4 is not listed on the TSCA inventory. It is for research and development use only.
SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 9/02/1997 Revision #8 Date: 2/10/2005 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.

SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR UN 1544
WGK Germany 3
Packaging Group III

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 Synonyms

N-methylephedrine
(1R,2S)-(-)-N-Methylephedrine
(aR)-a-[(1S)-1-(Dimethylamino)ethyl]benzenemethanol
EINECS 209-022-7
(-)-N-Methylephedrine
methyl-3-hydroxy-4-methylpentanoate
methylephedrine
Pentanoic acid,3-hydroxy-4-methyl-,methyl ester
[R-(R*,S*)]-a-[1-(Dimethylamino)ethyl]benzenemethanol
(1R,2S)-2-Dimethylamino-1-phenylpropanol
N,N-Dimethylnorephedrine
Benzenemethanol, α-[(1S)-1-(dimethylamino)ethyl]-, (αR)-
L-N-Methylephedrine
(1R,2S)-2-(Dimethylamino)-1-phenyl-1-propanol
(1R,2S)-(−)-N-Methylephedrine
erythro-a-[1-(Dimethylamino)ethyl]benzyl Alcohol
N-Methyl-L-ephedrine
(1R,2S)-N-Methylephedrine
MFCD00004504
(1R,2S)-3-Dimethylamino-1-phenyl-1-propanol
(1R,2S)-2-(dimethylamino)-1-phenylpropan-1-ol
(−)-(1R,2S)-2-Dimethylamino-1-phenylpropanol