AMMONIUM TETRATHIOMOLYBDATE
AMMONIUM TETRATHIOMOLYBDATE structure
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Common Name | AMMONIUM TETRATHIOMOLYBDATE | ||
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| CAS Number | 15060-55-6 | Molecular Weight | 260.29700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | H8MoN2S4 | Melting Point | >300 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Ion-pair chromatography coupled to inductively coupled plasma-mass spectrometry (IPC-ICP-MS) as a method for thiomolybdate speciation in natural waters.
Anal. Chem. 87(6) , 3388-95, (2015) Molybdenum precipitates preferentially under reducing conditions; therefore, its occurrence in sediment records is used as an indicator of paleoredox conditions. Although thiomolybdates (MoO4-xSx(2-) with x = 1-4) supposedly are necessary intermediates in the... |
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Potentiation of antibiofilm activity of amphotericin B by superoxide dismutase inhibition.
Oxid. Med. Cell. Longev. 2013 , 704654, (2013) This study demonstrates a role for superoxide dismutases (Sods) in governing tolerance of Candida albicans biofilms to amphotericin B (AmB). Coincubation of C. albicans biofilms with AmB and the Sod inhibitors N,N'-diethyldithiocarbamate (DDC) or ammonium tet... |
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Regio- and stereospecific synthesis of beta-sulfonamidodisulfides and beta-sulfonamidosulfides from aziridines using tetrathiomolybdate as a sulfur transfer reagent.
J. Org. Chem. 72 , 2106, (2007) A comprehensive study of a general and effective one-step procedure for the synthesis of beta-sulfonamidodisulfides directly from N-tosyl aziridines in a regio- and stereospecific manner under neutral conditions without the use of any Lewis acid or base has b... |
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Copper lowering therapy with tetrathiomolybdate as an antiangiogenic strategy in cancer.
Curr. Cancer Drug Targets 5 , 195, (2005) Tetrathiomolybdate (TM) is a novel anticopper agent under development for use in Wilson's disease. It acts by forming a stable tripartite complex with serum albumin and copper, rendering the complexed copper unavailable for cellular uptake. TM is a very poten... |
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Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C.
BMC Cancer 12 , 147, (2012) Our recent study showed that tetrathiomolybdate (TM), a drug to treat copper overload disorders, can sensitize drug-resistant endometrial cancer cells to reactive oxygen species (ROS)-generating anticancer drug doxorubicin. To expand these findings in the pre... |
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Flower-like PEGylated MoS2 nanoflakes for near-infrared photothermal cancer therapy.
Sci. Rep. 5 , 17422, (2015) Photothermal cancer therapy has attracted considerable interest for cancer treatment in recent years, but the effective photothermal agents remain to be explored before this strategy can be applied clinically. In this study, we therefore develop flower-like m... |
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Zinc is a novel intracellular second messenger.
J. Cell Biol. 177 , 637-45, (2007) Zinc is an essential trace element required for enzymatic activity and for maintaining the conformation of many transcription factors; thus, zinc homeostasis is tightly regulated. Although zinc affects several signaling molecules and may act as a neurotransmi... |
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Sur7 promotes plasma membrane organization and is needed for resistance to stressful conditions and to the invasive growth and virulence of Candida albicans.
MBio 3 , (2011) The human fungal pathogen Candida albicans causes lethal systemic infections because of its ability to grow and disseminate in a host. The C. albicans plasma membrane is essential for virulence by acting as a protective barrier and through its key roles in in... |
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Flexible membranes of MoS2/C nanofibers by electrospinning as binder-free anodes for high-performance sodium-ion batteries.
Sci. Rep. 5 , 9254, (2015) A flexible membrane consisting of MoS2/carbon nanofibers has been fabricated by a simple electrospinning method. MoS2 nanosheets are uniformly encapsulated in the inter-connected carbon nanofibers with diameters of ~150 nm. When evaluated as a binder-free ele... |
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Copper induces--and copper chelation by tetrathiomolybdate inhibits--endothelial activation in vitro.
Redox Rep. 19(1) , 40-8, (2014) Endothelial activation with increased expression of cellular adhesion molecules and chemokines critically contributes to vascular inflammation and atherogenesis. Redox-active transition metal ions play an important role in vascular oxidative stress and inflam... |