5alpha-Androst-16-en-3alpha-ol
5alpha-Androst-16-en-3alpha-ol structure
|
Common Name | 5alpha-Androst-16-en-3alpha-ol | ||
|---|---|---|---|---|
| CAS Number | 1153-51-1 | Molecular Weight | 274.44100 | |
| Density | 1.037 g/cm3 | Boiling Point | 374.1ºC at 760 mmHg | |
| Molecular Formula | C19H30O | Melting Point | 140-141ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 156.5ºC | |
|
β-cyclodextrin in personal care formulations: role on the complexation of malodours causing molecules.
Int. J. Cosmet. Sci. 37 , 438-45, (2015) The aim of this study was to prove the capability of β-cyclodextrin (β-CD) to interact with some representative molecules responsible to cause body malodour, such as carboxylic acids, thiols and steroids, present in sweat and body secretions.The association c... |
|
|
The pheromone androstenol (5 alpha-androst-16-en-3 alpha-ol) is a neurosteroid positive modulator of GABAA receptors.
J. Pharmacol. Exp. Ther. 317(2) , 694-703, (2006) Androstenol is a steroidal compound belonging to the group of odorous 16-androstenes, first isolated from boar testes and also found in humans. Androstenol has pheromone-like properties in both animals and humans, but the molecular targets of its pheromonal a... |
|
|
Molecular endocrinology. Two orphans find a home.
Nature 395(6702) , 543-4, (1998)
|
|
|
Ligand specificity of constitutive androstane receptor as probed by induced-fit docking and mutagenesis.
J. Med. Chem. 51 , 7119-31, (2008) Constitutive androstane receptor (CAR, NR1I3) belongs to the nuclear receptor family of transcription factors and acts as a chemical sensor of drugs and endogenous compounds. The ligand-binding preferences of CAR are diverse, and more importantly, there are s... |
|
|
Positive relationship between menstrual synchrony and ability to smell 5alpha-androst-16-en-3alpha-ol.
Chem. Senses 25(4) , 407-11, (2000) To explore the possibility that compounds which were identified as pheromones in experimental animals mediate human menstrual synchrony, we examined the relationship between menstrual synchrony and the ability to smell putative pheromones, 5alpha-androst-16-e... |
|
|
Determination of the deuterium/hydrogen ratio of endogenous urinary steroids for doping control purposes.
Rapid Commun. Mass Spectrom. 23 , 1917-26, (2009) The development and application of a combined gas chromatography/thermal conversion/isotope ratio mass spectrometry (GC/TC/IRMS) method for D/H ratio determination of endogenous urinary steroids are presented. The key element in sample preparation was the con... |
|
|
Determination of 5alpha-androst-16-en-3alpha-ol in truffle fermentation broth by solid-phase extraction coupled with gas chromatography-flame ionization detector/electron impact mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 870 , 209-15, (2008) A novel method using solid-phase extraction coupled with gas chromatography and flame ionization detector (FID)/electron impact mass spectrometry (EIMS) was developed for the determination of 5alpha-androst-16-en-3alpha-ol (androstenol), a steroidal compound ... |
|
|
Crystallographic analysis of murine constitutive androstane receptor ligand-binding domain complexed with 5alpha-androst-16-en-3alpha-ol.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 61 , 156-9, (2005) The constitutive androstane receptor (CAR) is a member of the nuclear receptor superfamily. In contrast to classical nuclear receptors, which possess small-molecule ligand-inducible activity, CAR exhibits constitutive transcriptional activity in the apparent ... |
|
|
[Synthesis of mammalian pheromone 5 alpha-androst-16-en-3-one and 5 alpha-Androst-16-en-3 alpha-ol].
Yao Xue Xue Bao 17(9) , 696-8, (1982)
|
|
|
Effects of 5alpha-androst-16-en-3alpha-ol on the pulsatile secretion of luteinizing hormone in human females.
Chem. Senses 25(4) , 465-7, (2000) We examined the effects of 5alpha-androst-16-en-3alpha-ol (3alpha-androstenol) on pulsatile luteinizing hormone (LH) secretion in human females. The frequency of the LH pulse in the follicular phase was decreased by exposing the women to 3alpha-androstenol. |