Ethyl N-Boc-4-methylpiperidine-4-carboxylate

Ethyl N-Boc-4-methylpiperidine-4-carboxylate Structure
Ethyl N-Boc-4-methylpiperidine-4-carboxylate structure
Common Name Ethyl N-Boc-4-methylpiperidine-4-carboxylate
CAS Number 189442-87-3 Molecular Weight 271.35300
Density 1.0134 Boiling Point 329.7ºC at 760mmHg
Molecular Formula C14H25NO4 Melting Point N/A
MSDS Chinese USA Flash Point 110ºC
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

Facile synthesis of 4-substituted-4-aminopiperidine derivatives, the key building block of piperazine-based CCR5 antagonists.

Bioorg. Med. Chem. Lett. 14 , 3675, (2004)

4-Substituted-4-aminopiperidine is an interesting structural motif found in a number of bioactive compounds. An efficient and convenient method for the synthesis of 4-differently substituted-4-aminopiperidine derivatives was described, employing isonipecotate...