Ethyl N-Boc-4-methylpiperidine-4-carboxylate

Modify Date: 2025-08-23 11:24:36

Ethyl N-Boc-4-methylpiperidine-4-carboxylate structure	Common Name	Ethyl N-Boc-4-methylpiperidine-4-carboxylate
	CAS Number	189442-87-3	Molecular Weight	271.35300
	Density	1.0134	Boiling Point	329.7ºC at 760mmHg
	Molecular Formula	C₁₄H₂₅NO₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	110ºC
	Symbol	GHS05, GHS06	Signal Word	Danger

Name	1-O-tert-butyl 4-O-ethyl 4-methylpiperidine-1,4-dicarboxylate
Synonym	More Synonyms

Density	1.0134
Boiling Point	329.7ºC at 760mmHg
Molecular Formula	C₁₄H₂₅NO₄
Molecular Weight	271.35300
Flash Point	110ºC
Exact Mass	271.17800
PSA	55.84000
LogP	2.52620
Vapour Pressure	0.000175mmHg at 25°C
Index of Refraction	1.4554

MSDS(Chinese)

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H301-H315-H318-H335
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T: Toxic;
Risk Phrases	R25;R37/38;R41
Safety Phrases	26-36/37/39-45
RIDADR	UN 2810
Hazard Class	6.1
HS Code	2933399090

Ethyl N-Boc-pip...

CAS#:142851-03-4

methyl iodide

CAS#:74-88-4

~99%

Ethyl N-Boc-4-m...

CAS#:189442-87-3

Literature: ARRAY BIOPHARMA INC. Patent: WO2008/121687 A2, 2008 ; Location in patent: Page/Page column 43; 89; 94 ; WO 2008/121687 A2

methyl iodide

CAS#:74-88-4

Ethyl N-Boc-4-m...

CAS#:189442-87-3

Literature: WO2005/30209 A1, ; Page/Page column 46 ; WO 2005/030209 A1

Precursor 2
CAS#:142851-03-4 Ethyl N-Boc-pip... CAS#:74-88-4 methyl iodide
DownStream 8
CAS#:343788-67-0 1-Boc-4-methylp... CAS#:343788-69-2 4-Amino-4-methy... CAS#:103039-88-9 ETHYL4-METHYLPI... CAS#:225240-71-1 Ethyl 4-methylp...
CAS#:297172-16-8 (4-Methyl-4-pip... CAS#:189321-63-9 1-Boc-4-methylp... CAS#:162648-32-0 4-Methyl-4-pipe... CAS#:389889-80-9 2-Methyl-2-Prop...

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Facile synthesis of 4-substituted-4-aminopiperidine derivatives, the key building block of piperazine-based CCR5 antagonists.

Bioorg. Med. Chem. Lett. 14 , 3675, (2004)

4-Substituted-4-aminopiperidine is an interesting structural motif found in a number of bioactive compounds. An efficient and convenient method for the synthesis of 4-differently substituted-4-aminopi...

1-BOC-4-METHYL-ISONIPECOTIC ACID ETHYL ESTER

N-tert-butoxycarbonyl-4-methylisonipecotic acid ethyl ester

4-methyl-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethvl ester

1-tert-Butyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate

Ethyl N-Boc-4-methylpiperidine-4-carboxylate

1-BOC-4-METHYLPIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER

Ethyl N-Boc-4-Methylpiperidine-4-Carboxylate

4-methyl piperidine-1,4-dicarboxylic acid-1-tert-butylester 4-ethyl ester

4-Methyl-1,4-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 4-ethyl ester

Ethyl 1-N-Boc-4-methyl-piperidine-carboxylate

ethyl N-t-butoxycarbonyl-4-methylpiperidine-4-carboxylate

O1-tert-butyl O4-ethyl 4-methylpiperidine-1,4-dicarboxylate