4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester

Modify Date: 2024-01-28 06:41:16

4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester Structure
4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester structure
Common Name 4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester
CAS Number 343788-69-2 Molecular Weight 214.305
Density 1.0±0.1 g/cm3 Boiling Point 283.0±33.0 °C at 760 mmHg
Molecular Formula C11H22N2O2 Melting Point N/A
MSDS N/A Flash Point 125.0±25.4 °C

 Names

Name tert-butyl 4-amino-4-methylpiperidine-1-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 283.0±33.0 °C at 760 mmHg
Molecular Formula C11H22N2O2
Molecular Weight 214.305
Flash Point 125.0±25.4 °C
Exact Mass 214.168121
PSA 55.56000
LogP 1.21
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.478

 Safety Information

HS Code 2933399090

 Synthetic Route

~93%

4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester Structure

4-Amino-4-methy...

CAS#:343788-69-2

Literature: PURDUE PHARMA L.P.; SHIONOGI and CO., LTD. Patent: WO2008/89201 A2, 2008 ; Location in patent: Page/Page column 234-235 ; WO 2008/089201 A2

~97%

4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester Structure

4-Amino-4-methy...

CAS#:343788-69-2

Literature: GLAXO GROUP LIMITED Patent: WO2008/119718 A1, 2008 ; Location in patent: Page/Page column 45 ; WO 2008/119718 A1

~99%

4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester Structure

4-Amino-4-methy...

CAS#:343788-69-2

Literature: VERTEX PHARMACEUTICALS INCORPORATED Patent: US2010/137305 A1, 2010 ; Location in patent: Page/Page column 37 ;

~%

4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester Structure

4-Amino-4-methy...

CAS#:343788-69-2

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 14 p. 3675 - 3678

~%

4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester Structure

4-Amino-4-methy...

CAS#:343788-69-2

Literature: Organic Process Research and Development, , vol. 13, # 6 p. 1145 - 1155

~%

4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester Structure

4-Amino-4-methy...

CAS#:343788-69-2

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 14 p. 3675 - 3678

~%

4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester Structure

4-Amino-4-methy...

CAS#:343788-69-2

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 14 p. 3675 - 3678

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-Amino-1-N-boc-4-methyl-piperidine
N'-butoxycarbonyl-4-methyl-4-aminopiperidine
4-amino-1-n-tert-butyloxycarbonyl-4-methyl-piperidine
4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester
1-Boc-4-Amino-4-methylpiperidine
tert-butyl-4-amino-4-methylpiperidine-1-carboxylate
1,1-dimethylethyl 4-amino-4-methyl-1-piperidinecarboxylate
N1-Boc-4-amino-4-methylpiperidine
4-amino-4-methyl-piperidine-1-carboxylic acid tert-butyl ester
4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE
4-Amino-4-methyl-1-Boc-piperidine
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