Dansylcadaverine
Dansylcadaverine structure
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Common Name | Dansylcadaverine | ||
|---|---|---|---|---|
| CAS Number | 10121-91-2 | Molecular Weight | 335.46400 | |
| Density | 1.19g/cm3 | Boiling Point | 505.5ºC at 760mmHg | |
| Molecular Formula | C17H25N3O2S | Melting Point | 137-140ºC | |
| MSDS | Chinese USA | Flash Point | 259.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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SUMO1 promotes Aβ production via the modulation of autophagy.
Autophagy 11(1) , 100-12, (2015) Autophagy is one of the main mechanisms in the pathophysiology of neurodegenerative disease. The accumulation of autophagic vacuoles (AVs) in affected neurons is responsible for amyloid-β (Aβ) production. Previously, we reported that SUMO1 (small ubiquitin-li... |
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Cadherin-6B undergoes macropinocytosis and clathrin-mediated endocytosis during cranial neural crest cell EMT.
J. Cell Sci. 128 , 1773-86, (2015) The epithelial-to-mesenchymal transition (EMT) is important for the formation of migratory neural crest cells during development and is co-opted in human diseases such as cancer metastasis. Chick premigratory cranial neural crest cells lose intercellular cont... |
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Reactive oxygen species and autophagy associated apoptosis and limitation of clonogenic survival induced by zoledronic acid in salivary adenoid cystic carcinoma cell line SACC-83.
PLoS ONE 9(6) , e101207, (2014) Salivary adenoid cystic carcinoma is an epithelial tumor in the head and neck region. Despite its slow growth, patients with salivary adenoid cystic carcinoma exhibit poor long term survival because of a high rate of distant metastasis. Lung and bone are comm... |
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Autophagy-Lysosome Pathway in Renal Tubular Epithelial Cells Is Disrupted by Advanced Glycation End Products in Diabetic Nephropathy.
J. Biol. Chem. 290 , 20499-510, (2015) It has been suggested that autophagy protects renal tubular epithelial cells (TECs) from injury in diabetic nephropathy (DN). However, the manner in which the autophagy-lysosome pathway is changed in this state remains unclear. In this study of DN, we investi... |
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Attenuation of vesicular stomatitis virus infection of brain using antiviral drugs and an adeno-associated virus-interferon vector.
Virology 475 , 1-14, (2014) Vesicular stomatitis virus (VSV) shows promise as a vaccine-vector and oncolytic virus. However, reports of neurotoxicity of VSV remain a concern. We compared 12 antiviral compounds to control infection of VSV-CT9-M51 and VSV-rp30 using murine and human brain... |
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p8 attenuates the apoptosis induced by dihydroartemisinin in cancer cells through promoting autophagy.
Cancer Biol. Ther. 16 , 770-9, (2015) Dihydroartemisinin (DHA) exhibits anticancer activities in a variety of cancer cells, but DHA alone are not effective enough for cancer therapy. In this study we found the stress-regulated protein p8 was obviously increased after DHA treatment in several canc... |
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AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells.
Int. J. Oncol. 42(3) , 993-1000, (2013) Baicalin is one of the major compounds in the traditional Chinese medicinal herb from Scutellaria baicalensis Georgi. We investigated the molecular mechanisms of cell autophagy induced by baicalin in human bladder cancer T24 cells. Baicalin inhibited cell sur... |
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Internalization by multiple endocytic pathways and lysosomal processing impact maspin-based therapeutics.
Mol. Cancer Res. 12(10) , 1480-91, (2014) Patients with metastatic disease face high rates of mortality with a paucity of therapeutic options. Protein-based therapeutics provide advantages over traditional chemotherapy through increased specificity, decreased immune impairment, and more direct means ... |
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Interactions of lecithinized superoxide dismutase with serum proteins and cells.
J. Pharm. Sci. 103(7) , 1987-94, (2014) Superoxide dismutase covalently bound to four lecithin molecules (PC-SOD) is known to be retained in circulating blood for a prolonged period and has a high affinity for cells, resulting in beneficial therapeutic effects in animal disease models. In this stud... |
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Glucosamine protects nucleus pulposus cells and induces autophagy via the mTOR-dependent pathway.
J. Orthop. Res. 32(11) , 1532-42, (2014) Although glucosamine has been suggested to be effective in the treatment of osteoarthritis, its effect on disc degeneration remains unclear. We sought to explore whether glucosamine can activate autophagy in rat nucleus pulposus (NP) cells and protect cells t... |