SCS

SCS Structure
SCS structure
Common Name SCS
CAS Number 3232-36-8 Molecular Weight 256.25700
Density 1.406g/cm3 Boiling Point 427.3ºC at 760mmHg
Molecular Formula C14H12N2O3 Melting Point 280-284°C
MSDS Chinese USA Flash Point 212.2ºC
Symbol GHS07
GHS07
Signal Word Warning

Cytotoxicity of salicylaldehyde benzoylhydrazone analogs and their transition metal complexes: quantitative structure-activity relationships.

J. Inorg. Biochem. 77 , 125-133 , (1999)

A series of salicylaldehyde benzoylhydrazone derivatives, their copper(II) complexes and a range of transition metal complexes of the unsubstituted ligand has been synthesized and evaluated for cytotoxicity against a human adenocarcinoma cell line. A QSAR ana...

Salicylidene salicylhydrazide, a selective inhibitor of beta 1-containing GABAA receptors.

Br. J. Pharmacol. 142 , 97-106 , (2004)

1. A high-throughput assay utilizing the voltage/ion probe reader (VIPR) technology identified salicylidene salicylhydrazide (SCS) as being a potent selective inhibitor of alpha2beta1gamma1 GABA(A) receptors with a maximum inhibition of 56+/-5% and an IC(50) ...

GABAA receptor subunit beta1 is involved in the formation of protease-resistant prion protein in prion-infected neuroblastoma cells.

FEBS Lett. 584(6) , 1193-8, (2010)

Gamma-aminobutyric acid type A (GABAA) receptor beta1 (gabrb1), a subunit of GABAA receptors involved in inhibitory effects on neurotransmission, was found to associate with the formation of protease-resistant prion protein in prion-infected neuroblastoma cel...