Iminodiacetic acid

Iminodiacetic acid Structure
Iminodiacetic acid structure
Common Name Iminodiacetic acid
CAS Number 142-73-4 Molecular Weight 133.10
Density 1.4±0.1 g/cm3 Boiling Point 370.6±27.0 °C at 760 mmHg
Molecular Formula C4H7NO4 Melting Point 243 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 177.9±23.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Selective Solid-Phase Extraction of Zinc(II) from Environmental Water Samples Using Ion Imprinted Activated Carbon.

J. AOAC Int. 98(1) , 206-12, (2015)

A simple ion imprinted amino-functionalized sorbent was synthesized by coupling activated carbon with iminodiacetic acid, a functional compound for metal chelating, through cyanoric chloride spacer. The resulting sorbent has been characterized using FTIR spec...

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

J. Med. Chem. 51 , 6740-51, (2008)

The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared and assayed 33 coumarin derivatives, and the theoretical pr...

Immobilized metal affinity chromatography using open tubular capillary for phosphoprotein analysis: comparison between polymer brush coating and surface functionalization.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(27) , 2852-9, (2011)

In the present article, open tubular-IMAC columns, functionalized by iminodiacetic acid (IDA) for the immobilization of Fe(3+), were prepared by in situ chemical modification of fused silica capillary using two chemistries, polymer brush coating and surface f...

Capillary isoelectric focusing method development and validation for investigation of recombinant therapeutic monoclonal antibody.

J. Pharm. Biomed. Anal. 114 , 53-61, (2015)

Capillary isoelectric focusing (cIEF) is a basic and highly accurate routine analytical tool to prove identity of protein drugs in quality control (QC) and release tests in biopharmaceutical industries. However there are some "out-of-the-box" applications com...

EPOR-Based Purification and Analysis of Erythropoietin Mimetic Peptides from Human Urine by Cys-Specific Cleavage and LC/MS/MS.

J. Am. Soc. Mass Spectrom. 26 , 1617-25, (2015)

The development of a new class of erythropoietin mimetic agents (EMA) for treating anemic conditions has been initiated with the discovery of oligopeptides capable of dimerizing the erythropoietin (EPO) receptor and thus stimulating erythropoiesis. The most p...

Synthesis and characterization of poly[N-isopropylacrylamide-co-1-(N,N-bis-carboxymethyl)amino-3-allylglycerol] grafted to magnetic nano-particles for the extraction and determination of fluvoxamine in biological and pharmaceutical samples.

J. Chromatogr. A. 1345 , 37-42, (2014)

In this research, a novel method is reported for the surface grafting of N-isopropylacrylamide as a thermosensitive agent and 1-(N,N-bis-carboxymethyl)amino-3-allylglycerol with an affinity toward fluvoxamine onto magnetic nano-particles modified by 3-mercapt...

Determination of aminopolycarboxylic acids at ultra-trace levels by means of online coupling ion exchange chromatography and inductively coupled plasma-mass spectrometry with indirect detection via their Pd²⁺-complexes.

Anal. Chim. Acta 884 , 124-32, (2015)

A new indirect IC-ICP-MS method for the determination of aminopolycarboxylic acids in water samples is described. It is based on the addition of an excess of Pd(II) to water samples. The analytes are forced into very strong and negatively charged palladium co...

Assessment and modelling of Ni(II) retention by an ion-imprinted polymer: application in natural samples.

J. Colloid. Interface Sci. 448 , 473-81, (2015)

Three novel Ni(II)-Ion-Imprinted Polymer (IIP) were synthesized by precipitation polymerization of ethylene glycol dimethacrylate (crosslinker) with a complex of nickel(II) and vinylbenzyl iminodiacetic acid (VbIDA). The three IIPs were prepared with various ...

Myoglobin-directed assemblies of binary monolayers functionalized with iminodiacetic acid ligands at the air-water interface through metal coordination for multivalent protein binding.

Phys. Chem. Chem. Phys. 14(16) , 5470-8, (2012)

Myoglobin binding to the binary monolayers composed of sodium hexadecylimino diacetate and hexadecanol at the air-water interface by means of metal coordination has been investigated using infrared reflection absorption spectroscopy (IRRAS). In the absence of...

Integrative refolding and purification of histidine-tagged protein by like-charge facilitated refolding and metal-chelate affinity adsorption.

J. Chromatogr. A. 1344 , 59-65, (2014)

This work proposed an integrative method of protein refolding and purification by like-charged resin facilitated refolding and metal-chelate affinity adsorption. Hexahistidine-tagged enhanced green fluorescence protein (EGFP) was overexpressed in Escherichia ...