Ibotenic acid

Ibotenic acid Structure
Ibotenic acid structure
Common Name Ibotenic acid
CAS Number 2552-55-8 Molecular Weight 158.112
Density 1.7±0.1 g/cm3 Boiling Point 458.8±45.0 °C at 760 mmHg
Molecular Formula C5H6N2O4 Melting Point 141-147 °C
MSDS Chinese USA Flash Point 231.3±28.7 °C
Symbol GHS06
GHS06
Signal Word Danger

Audition-independent vocal crystallization associated with intrinsic developmental gene expression dynamics.

J. Neurosci. 35(3) , 878-89, (2015)

Complex learned behavior is influenced throughout development by both genetic and environmental factors. Birdsong, like human speech, is a complex vocal behavior acquired through sensorimotor learning and is based on coordinated auditory input and vocal outpu...

Assessment of sensorimotor gating following selective lesions of cholinergic pedunculopontine neurons.

Eur. J. Neurosci. 40(10) , 3526-37, (2014)

Sensorimotor gating is the state-dependent transfer of sensory information into a motor system. When this occurs at an early stage of the processing stream it enables stimuli to be filtered out or partially ignored, thereby reducing the demands placed on adva...

Dopamine D2 Modulation of Sign and Goal Tracking in Rats.

Neuropsychopharmacology 40 , 2096-102, (2015)

In Pavlovian conditioning, sign- and goal-tracking behaviors represent different approaches towards the conditioned stimulus. These behavioral patterns have been associated with predictive or incentive properties of the conditioned stimulus, with a crucial in...

The sigma agonist 1,3-di-o-tolyl-guanidine reduces the morphological and behavioral changes induced by neonatal ventral hippocampus lesion in rats.

Synapse 69(4) , 213-25, (2015)

Sigma (σ) receptors have generated a great deal of interest due to their possible role in psychosis, neuroprotection, and various other behaviors including addictive processes. Sigma receptors have been located in brain areas involved in motor functions, incl...

Effect of antidepressant drugs on the vmPFC-limbic circuitry.

Neuropharmacology 92 , 116-24, (2015)

Our recent study indicates that the lesions of the prefrontal cortex in rats result in depressive-like behavior in forced swim test and REM sleep alterations, two well-established biomarkers of depression disorder. We hypothesized that antidepressants may tar...

Unilateral lesion of the nigrostriatal pathway decreases the response of GABA interneurons in the dorsal raphe nucleus to 5-HT(1A) receptor stimulation in the rat.

Neurochem. Int. 61(8) , 1344-56, (2012)

This study examined the firing rate and pattern of electrophysiologically and chemically identified GABA interneurons in the dorsal raphe nucleus (DRN), and role of 5-HT(1A) receptor agonist 8-OH-DPAT and the medial prefrontal cortex (mPFC) in the firing acti...

Fungal hallucinogens psilocin, ibotenic acid, and muscimol: analytical methods and biologic activities.

Ther. Drug Monit. 35(4) , 420-42, (2013)

Psychoactive drugs of fungal origin, psilocin, ibotenic acid, and muscimol among them have been proposed for recreational use and popularized since the 1960s, XX century. Despite their well-documented neurotoxicity, they reached reputation of being safe and n...

The head direction cell system and behavior: The effects of lesions to the lateral mammillary bodies on spatial memory in a novel landmark task and in the water maze.

Behav. Neurosci. 129 , 709-19, (2015)

The head direction system is composed of neurons found in a number of connected brain areas that fire in a sharply tuned, directional way. The function of this system, however, has not been fully established. To assess this, we devised a novel spatial landmar...

[Clinical toxicology of mushroom poisoning. Amanita pantherina, Amanita ibotengutake].

Chudoku. Kenkyu. 26(3) , 219-22, (2013)

Cyclin D1 is required for proliferation of Olig2-expressing progenitor cells in the injured cerebral cortex.

Glia 61(9) , 1443-55, (2013)

Little is known about the molecular mechanisms driving proliferation of glial cells after an insult to the central nervous system (CNS). To test the hypothesis that the G1 regulator cyclin D1 is critical for injury-induced cell division of glial cells, we app...