NS-2028
NS-2028 structure
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Common Name | NS-2028 | ||
|---|---|---|---|---|
| CAS Number | 204326-43-2 | Molecular Weight | 269.052 | |
| Density | 2.1±0.1 g/cm3 | Boiling Point | 353.8±52.0 °C at 760 mmHg | |
| Molecular Formula | C9H5BrN2O3 | Melting Point | 161-162ºC | |
| MSDS | USA | Flash Point | 167.8±30.7 °C | |
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Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus.
Neuropharmacology 99 , 422-31, (2015) Nitric oxide (NO) is involved in desensitization of μ-opioid receptors (MOR). We used extracellular recordings in vitro to unmask the NO-dependent pathways involved in MOR desensitization in the rat locus coeruleus (LC). Perfusion with ME (3 and 10 μM) concen... |
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Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase.
Br. J. Pharmacol. 123 , 299-309, (1998) 1 The haeme-containing soluble guanylyl cyclase (alpha1beta1-heterodimer) is a major intracellular receptor and effector for nitric oxide (NO) and carbon monoxide (CO) and mediates many of their biological actions by increasing cyclic GMP. We have synthesized... |
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