Purine
Purine structure
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Common Name | Purine | ||
|---|---|---|---|---|
| CAS Number | 120-73-0 | Molecular Weight | 120.112 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 424ºC at 760mmHg | |
| Molecular Formula | C5H4N4 | Melting Point | 214-217 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 225.4ºC | |
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Assessing the metabolic impact of nitrogen availability using a compartmentalized maize leaf genome-scale model.
Plant Physiol. 166(3) , 1659-74, (2014) Maize (Zea mays) is an important C4 plant due to its widespread use as a cereal and energy crop. A second-generation genome-scale metabolic model for the maize leaf was created to capture C4 carbon fixation and investigate nitrogen (N) assimilation by modelin... |
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Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry.
Electrophoresis 35(23) , 3321-30, (2014) There is high interest in the discovery of early diagnostic biomarkers of Alzheimer's disease, for which metabolomics exhibits a great potential. In this work, a metabolomic approach based on ultrafiltration and analysis by CE-MS has been used to obtain repre... |
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The presence of fucogalactoxyloglucan and its synthesis in rice indicates conserved functional importance in plants.
Plant Physiol. 168 , 549-60, (2015) The predominant structure of the hemicellulose xyloglucan (XyG) found in the cell walls of dicots is a fucogalactoXyG with an XXXG core motif, whereas in the Poaceae (grasses and cereals), the structure of XyG is less xylosylated (XXGGn core motif) and lacks ... |
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A Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantum.
PLoS ONE 10 , e0130675, (2015) There is a rising resistance against antimony drugs, the gold-standard for treatment until some years ago. That is a serious problem due to the paucity of drugs in current clinical use. In a research to reveal how these drugs affect the parasite during treatm... |
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Metabolomics analysis of metabolic effects of nicotinamide phosphoribosyltransferase (NAMPT) inhibition on human cancer cells.
PLoS ONE 9(12) , e114019, (2014) Nicotinamide phosphoribosyltransferase (NAMPT) plays an important role in cellular bioenergetics. It is responsible for converting nicotinamide to nicotinamide adenine dinucleotide, an essential molecule in cellular metabolism. NAMPT has been extensively stud... |
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Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells.
Drug Des. Devel. Ther. 9 , 349-417, (2015) Plumbagin (PLB) has exhibited a potent anticancer effect in preclinical studies, but the molecular interactome remains elusive. This study aimed to compare the quantitative proteomic responses to PLB treatment in human prostate cancer PC-3 and DU145 cells usi... |
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Exploratory analysis of urinary tract infection using a GC-APCI-MS platform.
Analyst 140(8) , 2834-41, (2015) Urinary tract infection (UTI) is among the most common bacterial infections worldwide. The understanding of the physiological mechanisms affected by UTI may need modern integrative '-omics' technologies, and metabolomics in particular. Here we present the fir... |
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Interactions of corn meal or molasses with a soybean-sunflower meal mix or flaxseed meal on production, milk fatty acid composition, and nutrient utilization in dairy cows fed grass hay-based diets.
J. Dairy Sci. 98(1) , 443-57, (2014) We investigated the interactions of corn meal or molasses [nonstructural carbohydrate (NSC) supplements] with a soybean-sunflower meal mix or flaxseed meal [rumen-degradable protein (RDP) supplements] on animal production, milk fatty acids profile, and nutrie... |
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Pseudomonas fluorescens: identification of Fur-regulated proteins and evaluation of their contribution to pathogenesis.
Dis. Aquat. Organ. 115 , 67-80, (2015) Pseudomonas fluorescens is a Gram-negative bacterium and a common pathogen to a wide range of farmed fish. In a previous study, we found that the ferric uptake regulator gene (fur) is essential to the infectivity of a pathogenic fish isolate of P. fluorescens... |
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Subpathway-GMir: identifying miRNA-mediated metabolic subpathways by integrating condition-specific genes, microRNAs, and pathway topologies.
Oncotarget 6 , 39151-64, (2015) MicroRNAs (miRNAs) regulate disease-relevant metabolic pathways. However, most current pathway identification methods fail to consider miRNAs in addition to genes when analyzing pathways. We developed a powerful method called Subpathway-GMir to construct miRN... |