1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC

1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC Structure
1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC structure
Common Name 1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC
CAS Number 35418-58-7 Molecular Weight 782.08200
Density N/A Boiling Point N/A
Molecular Formula C44H80NO8P Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Miscibility of Sphingomyelins and Phosphatidylcholines in Unsaturated Phosphatidylcholine Bilayers.

Biophys. J. 109 , 1907-16, (2015)

Polyunsaturated phospholipids are common in biological membranes and affect the lateral structure of bilayers. We have examined how saturated sphingomyelin (SM; palmitoyl and stearoyl SM (PSM and SSM, respectively)) and phosphatidylcholine (PC; dipalmitoyl PC...

CTP:phosphocholine cytidylyltransferase activation by oxidized phosphatidylcholines correlates with a decrease in lipid order: a 2H NMR analysis.

Biochemistry 38(47) , 15606-14, (1999)

The enzyme CTP:phosphocholine cytidylyltransferase (CT) binds reversibly to membranes and is active only in its membrane-bound form. Membrane lipid composition influences the equilibrium between its soluble and membrane-bound forms. Whereas the enzyme is not ...

Characterization of hormonally regulated and particulate-associated phospholipase A2 from bovine endothelial cells.

J. Biol. Chem. 268(16) , 11697-702, (1993)

Hormonally regulated and particulate-associated phospholipase A2 (PLA2) was detected in endothelial cells from bovine pulmonary artery. The enzyme was solubilized and subjected to initial characterization. PLA2 activity was determined in subcellular fractions...

Preparation and characterization of 8a-(phosphatidylcholine-dioxy)-alpha-tocopherones and their formation during the peroxidation of phosphatidylcholine in liposomes.

Biosci. Biotechnol. Biochem. 62(7) , 1293-300, (1998)

alpha-Tocopherol was reacted with the phosphatidylcholines (PCs), 1-palmitoyl-2-linoleoyl-3-sn-PC (PLPC), 1-palmitoyl-2-linolenoyl-3-sn-PC, 1-palmitoyl-2-arachidonoyl-3-sn-PC (PAPC) and 1-stearoyl-2-arachidonoyl-3-sn-PC, in the presence of the free radical in...

Transfer of very low density lipoprotein-associated phospholipids to activated human platelets.

J. Lipid Res. 47(2) , 341-8, (2006)

LDL-associated phospholipids (PLs) may be transferred into platelets. In this work, we characterized the role of VLDLs as PL donors. VLDL transferred radiolabeled PLs to platelets in a temperature- and concentration-dependent manner. LPL stimulated this proce...

A novel phospholipase A2 activity in saliva of the lone star tick, Amblyomma americanum (L.).

Exp. Parasitol. 87(2) , 121-32, (1997)

Saliva from female lone star ticks, Amblyomma americanum, contained a novel phospholipase A2 (PLA2) activity that hydrolyzed 14C-arachidonate from 14C-arachidonyl phosphatidylcholine. The tick saliva PLA2 (ts-PLA2) was active over a broad pH range (4.5-11.5) ...

Peptidoglycan enhances secretion of monocyte chemoattractants via multiple signaling pathways.

Biochem. Biophys. Res. Commun. 408(1) , 132-8, (2011)

Peptidoglycan (PG) is detected in a high proportion in inflammatory cell-rich regions of human atheromatous plaques. In the present study, we determined the cellular factors involved in PG-mediated chemokine expression in mononuclear cells in order to underst...

Na,K-ATPase and phospholipid degradation in bovine and human lenses.

Curr. Eye Res. 11(5) , 459-67, (1992)

Na,K-ATPase, an enzyme intrinsic to the membrane of most cells, is inhibited in cataract. Na,K-ATPase, activity in clear non-cataractous lenses is found predominantly in the lens epithelium. The lens fiber cells would appear to be unique, among mammalian cell...

Enhancement of nitrogen dioxide-induced lipid peroxidation and DNA strand breaking by cysteine and glutathione.

Free Radic. Res. 21(6) , 399-408, (1994)

Nitrogen dioxide less than 100 ppm in air induced lipid peroxidation of liposome composed of 1-palmitoyl-2-arachidonylphosphatidylcholine as assessed by thiobarbituric acid reactivity. The nitrogen dioxide-induced lipid peroxidation was enhanced by cysteine, ...

Free radicals from 1-palmitoyl-2-arachidonoylphosphatidylcholine liposomes in Fe2+/ascorbic acid solution.

Biol. Pharm. Bull. 19(6) , 779-82, (1996)

The generation of free radicals during the lipid peroxidation of liposomes composed of 1-palmitoyl-2-arachidonoylphosphatidylcholine (PAPC-liposome) in Fe2+/ascorbic acid (AsA) solution was studied by the ESR spin trapping technique. A carbon-centered radical...