1,2,3,4-tetrachlorobenzene
1,2,3,4-tetrachlorobenzene structure
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Common Name | 1,2,3,4-tetrachlorobenzene | ||
|---|---|---|---|---|
| CAS Number | 634-66-2 | Molecular Weight | 215.89200 | |
| Density | 1,73 g/cm3 | Boiling Point | 254 °C761 mm Hg(lit.) | |
| Molecular Formula | C6H2Cl4 | Melting Point | 44 °C | |
| MSDS | Chinese USA | Flash Point | >230 °F | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.
Eur. J. Med. Chem. 43 , 714-40, (2008) Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and organic compounds of different classes by optimal descriptors.... |
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Determination of chlorobenzenes in water samples by solid-phase disk extraction and gas chromatography-electron capture detection.
J. Chromatogr. Sci. 52(5) , 375-82, (2014) A simple, rapid, sensitive and high throughput method is described, based on solid-phase disk extraction (SPDE) and gas chromatography-electron capture detection, for the determination of chlorobenzens (CBs) in water samples. The proposed SPDE sample pretreat... |
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Chlorocatechols substituted at positions 4 and 5 are substrates of the broad-spectrum chlorocatechol 1,2-dioxygenase of Pseudomonas chlororaphis RW71.
J. Bacteriol. 183(3) , 997-1011, (2001) The nucleotide sequence of a 10,528-bp region comprising the chlorocatechol pathway gene cluster tetRtetCDEF of the 1,2,3,4-tetrachlorobenzene via the tetrachlorocatechol-mineralizing bacterium Pseudomonas chlororaphis RW71 (T. Potrawfke, K. N. Timmis, and R.... |
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[The effect of some hexachlorobenzene catabolites on the porphyrin metabolism of rats (author's transl)].
Derm. Beruf Umwelt. 29(2) , 40-2, (1981) In answering the question as to what role possible metabolites of hexachlorobenzene play in the procreation of toxic hexachlorobenzene porphyria in rats, both pure hexachlorobenzene and different mixtures were fed to them. In each case 20% of the hexachlorobe... |
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A teratological evaluation and analysis of fetal tissue levels following administration of tetrachlorobenzene isomers to the rat.
Teratology 29(1) , 21-7, (1984) Three tetrachlorobenzene (TCB) congeners (1,2,3,4- 1,2,3,5-, and 1,2,4,5-) were administered daily by gavage to pregnant Sprague-Dawley rats at levels of 50, 100, or 200 mg/kg from day 6 through day 15 of gestation. Mothers were sacrificed on day 21 of gestat... |
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Comparative toxicity of 1,2,3,4-, 1,2,4,5-, and 1,2,3,5-tetrachlorobenzene in the rat: results of acute and subacute studies.
J. Toxicol. Environ. Health A 11(4-6) , 663-77, (1983) Groups of 10 male and 10 female rats were dosed orally with 1,2,3,4-, 1,2,4,5-, or 1,2,3,5-tetrachlorobenzene (TCB) at levels that ranged from 200 to 4000 mg/kg, and were observed clinically for 14 d. LD50 values for 1,2,3,4-, 1,2,4,5-, and 1,2,3,5-TCB were f... |
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Metabolism of 1,2,3,4-, 1,2,3,5-, and 1,2,4,5-tetrachlorobenzene in the rat.
J. Toxicol. Environ. Health A 13(4-6) , 777-86, (1984) Adult male rats were given orally single doses of 14C-labeled 1,2,3,4-, 1,2,3,5-, or 1,2,4,5-tetrachlorobenzene (TCB) at 10 mg/kg body weight, and were housed in individual metabolism cages to collect urine and feces for radioassay. For 1,2,3,4- and 1,2,3,5-T... |
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Toxicity of 1,2,3,4-, 1,2,3,5- and 1,2,4,5-tetrachlorobenzene in the rat: results of a 90-day feeding study.
Drug Chem. Toxicol. 7(2) , 113-27, (1984) Tetrachlorobenzenes (TCB) are industrial chemicals which have been used as intermediates for chemical synthesis and for electrical insulation. Recently TCB residues have been found in Great Lakes fish. The present study was designed to determine the subchroni... |
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Differential acute toxicity of tetrachlorobenzene isomers to oligochaetes in soil and water: application of the critical body residue concept.
Bull. Environ. Contam. Toxicol. 87(3) , 209-14, (2011) The acute, lethal potency of the 1,2,3,4-, 1,2,4,5- and 1,2,3,5-tetrachlorobenzene isomers was compared in the terrestrial and aquatic oligochaetes Eisenia andrei and Tubifex tubifex. 1,2,4,5-TeCB was neither lethal, nor produced any perceptible adverse effec... |
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Maternal hepatic and embryonic effects of 1,2,3,4-tetrachlorobenzene in the rat.
Toxicology 26(3-4) , 243-56, (1983) To assess possible maternal hepatic and reproductive effects of this uncharged, low molecular weight, lipophilic chlorinated benzene 0, 100, 300 and 1000 mg/kg/day of 1,2,3,4-tetrachlorobenzene (TCB) was orally administered to pregnant rats on days 9-13 of ge... |