H-Gly-Phe-βNA
H-Gly-Phe-βNA structure
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Common Name | H-Gly-Phe-βNA | ||
|---|---|---|---|---|
| CAS Number | 21438-66-4 | Molecular Weight | 347.41000 | |
| Density | 1.254g/cm3 | Boiling Point | 692.4ºC at 760mmHg | |
| Molecular Formula | C21H21N3O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 372.6ºC | |
| Symbol |
GHS08 |
Signal Word | Warning | |
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Effect of glycyl-L-phenylalanine 2-naphthylamide on invertase endocytosed by rat liver.
Biochem. J. 225(3) , 645-8, (1985) The release by glycyl-L-phenylalanine 2-naphthylamide (Gly-L-Phe-2-NNap) of endocytosed invertase associated with the MLP fraction (sum of the M, L and P fractions [de Duve, Pressman, Gianetto, Wattiaux & Appelmans (1955) Biochem. J. 63, 604-617]) of rat live... |
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Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes.
J. Cell Sci. 125(Pt 19) , 4567-75, (2012) Elucidating mechanisms by which Ca(2+) signals are generated by monocytes is important for understanding monocyte function in health and disease. We have investigated mechanisms underlying Ca(2+) signals generated following disruption of lysosomes by exposure... |
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Calcium mobilization by nicotinic acid adenine dinucleotide phosphate (NAADP) in rat astrocytes.
Cell Calcium 39(2) , 143-53, (2006) Nicotinic acid adenine dinucleotide phosphate (NAADP) has been shown to release intracellular Ca(2+) in several types of cells. We have used Ca(2+)-sensitive fluorescent dyes (Fura-2, Fluo-4) to measure intracellular Ca(2+) in astrocytes in culture and in sit... |
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A confocal study on the visualization of chromaffin cell secretory vesicles with fluorescent targeted probes and acidic dyes.
J. Struct. Biol. 172(3) , 261-9, (2010) Secretory vesicles have low pH and have been classically identified as those labelled by a series of acidic fluorescent dyes such as acridine orange or neutral red, which accumulate into the vesicles according to the pH gradient. More recently, several fusion... |
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N-acetylneuraminic acid accumulation in a buoyant lysosomal fraction of cultured fibroblasts from patients with infantile generalized N-acetylneuraminic acid storage disease.
Biochem. Biophys. Res. Commun. 139(2) , 838-44, (1986) Cultured fibroblasts from control individuals and two patients affected with the infantile variant of generalized N-acetylneuraminic acid (NeuAc) storage disease were disrupted by nitrogen cavitation, and the post-nuclear supernatant fractions were subjected ... |
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Expression and purification of active recombinant cathepsin C (dipeptidyl aminopeptidase I) of kuruma prawn Marsupenaeus japonicus in insect cells.
J. Biomed. Biotechnol. 2009 , 746289, (2009) Cathepsin C (CTSC) is a lysosomal cysteine protease belonging to the papain superfamily. Our previous study showed that CTSC precursor (zymogen) is localized exclusively in cortical rods (CRs) of mature oocyte in the kuruma prawn Marsupenaeus japonicus, sugge... |
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Uptake and intracellular fate of gelonin, a ribosome-inactivating protein, in rat liver.
Biochem. Biophys. Res. Commun. 296(5) , 1180-5, (2002) Gelonin, a type 1 ribosome-inactivating protein, has been used as toxin conjugate for several therapeutic purposes. We have investigated the endocytosis of gelonin by rat liver in vivo. Subcellular distribution of [125I]gelonin was established after different... |
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An improved procedure for the isolation of lamellar bodies from human lung. Lamellar bodies free of lysosomes contain a spectrum of lysosomal-type hydrolases.
Biochim. Biophys. Acta 922(3) , 259-69, (1987) We have recently shown that lamellar body fractions purified from human lung contain a distinct acid alpha-glucosidase distinguishable from lysosomal acid alpha-glucosidase in that it does not cross-react with antibodies raised against the lysosomal enzyme an... |
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Separation of lysosomes and autophagosomes by means of glycyl-phenylalanine-naphthylamide, a lysosome-disrupting cathepsin-C substrate.
Eur. J. Biochem. 221(1) , 595-602, (1994) In density-gradient analyses of autophagic vacuoles from isolated rat hepatocytes, autophagosomes could be recognized by the presence of an autophagically sequestered cytosolic enzyme, lactate dehydrogenase (LDH). Lysosomes were identified by marker enzymes s... |
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Use of glycyl-L-phenylalanine 2-naphthylamide, a lysosome-disrupting cathepsin C substrate, to distinguish between lysosomes and prelysosomal endocytic vacuoles.
Biochem. J. 300 ( Pt 1) , 229-36, (1994) Lysosome-disrupting enzyme substrates have been used to distinguish between lysosomal and prelysosomal compartments along the endocytic pathway in isolated rat hepatocytes. The cells were incubated for various periods of time with 125I-labelled tyramine cello... |