(1S,2R)-(+)-Norephedrine
(1S,2R)-(+)-Norephedrine structure
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Common Name | (1S,2R)-(+)-Norephedrine | ||
|---|---|---|---|---|
| CAS Number | 37577-28-9 | Molecular Weight | 187.667 | |
| Density | 1.071g/cm3 | Boiling Point | 288.1ºC at 760mmHg | |
| Molecular Formula | C9H13NO | Melting Point | 51-54ºC | |
| MSDS | USA | Flash Point | 235.4 °F | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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The Psychostimulant Khat (Catha edulis) Inhibits CYP2D6 Enzyme Activity in Humans.
J. Clin. Psychopharmacol. 35 , 694-9, (2015) The use of khat (Catha edulis) while on medication may alter treatment outcome. In particular, the influence of khat on the metabolic activities of drug-metabolizing enzymes is not known. We performed a comparative 1-way crossover study to evaluate the effect... |
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Solvent-free melting techniques for the preparation of lipid-based solid oral formulations.
Pharm. Res. 32(5) , 1519-45, (2015) Lipid excipients are applied for numerous purposes such as taste masking, controlled release, improvement of swallowability and moisture protection. Several melting techniques have evolved in the last decades. Common examples are melt coating, melt granulatio... |
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The Expected Net Present Value of Developing Weight Management Drugs in the Context of Drug Safety Litigation.
Pharmacoeconomics 33 , 749-63, (2015) Following withdrawals, failures, and significant litigation settlements, drug product launches in the anti-obesity category slowed despite a large and growing unmet need. Litigation concerns, a more risk-averse regulatory policy, and the difficulty of develop... |
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Forensic analysis of hallucinogenic mushrooms and khat (Catha edulis Forsk) using cation-exchange liquid chromatography.
Forensic Sci. Int. 195(1-3) , 160-4, (2010) Hallucinogenic mushrooms (e.g. Psilocybe and Panaeolus species) as well as leaves and young shoots of the khat tree (Catha edulis Forsk) are illicit drugs in many countries. The exact concentration of the hallucinogenic alkaloids psilocin and psilocybin in mu... |
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Keep an eye on the pupil: developing countries under chemical attack.
Intern. Emerg. Med. 4(3) , 231-3, (2009)
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The relevance of the urinary concentration of ephedrines in anti-doping analysis: determination of pseudoephedrine, cathine, and ephedrine after administration of over-the-counter medicaments.
Ther. Drug Monit. 31(4) , 520-6, (2009) This article describes a method for the detection and quantitation of cathine, pseudoephedrine, ephedrine, and methylephedrine in urine, using their deuterated analogues as internal standards and derivatization to form the corresponding trimethylsilyl derivat... |
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Cathine, an amphetamine-related compound, acts on mammalian spermatozoa via beta1- and alpha2A-adrenergic receptors in a capacitation state-dependent manner.
Hum. Reprod. 22(3) , 756-65, (2007) Mammalian spermatozoa have been shown to have beta(1,2,3)- and alpha(2A)-adrenergic receptors, the former functioning only in uncapacitated spermatozoa and the latter only in capacitated cells. Cathine, an amphetamine-related metabolite of a compound found in... |
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Determination of urinary concentrations of pseudoephedrine and cathine after therapeutic administration of pseudoephedrine-containing medications to healthy subjects: implications for doping control analysis of these stimulants banned in sport.
Drug Test. Anal. 4(5) , 320-9, (2012) Due to its stimulatory effects on the central nervous system, and its structural similarity to banned stimulants such as ephedrine and methamphetamine, pseudoephedrine (PSE) at high doses is considered as an ergogenic aid for boosting athletic performance. Ho... |
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Analysis of stimulants in oral fluid and urine by gas chromatography-mass spectrometry II: pseudophedrine.
J. Anal. Toxicol. 34(4) , 210-5, (2010) This study was designed to optimize a method for the identification and quantification of ephedrines in oral fluid (OF) and for its application to subjects taking different doses of pseudoephedrine. Ephedrines use by athletes is banned by World Anti-Doping Ag... |
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Extraction and microencapsulation of khat: effects on sexual motivation and estradiol level in female rats.
J. Sex. Med. 6(3) , 682-95, (2009) Khat (Catha edulis) is an evergreen tree/shrub that is thought to affect sexual motivation or libido. Its positive effect on sexual desire is more frequently observed in females than in males and occurs when khat is chewed. Thus, khat's effects on sexual beha... |