D-(-)-Tagatose
D-(-)-Tagatose structure
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Common Name | D-(-)-Tagatose | ||
|---|---|---|---|---|
| CAS Number | 87-81-0 | Molecular Weight | 180.156 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 551.7±50.0 °C at 760 mmHg | |
| Molecular Formula | C6H12O6 | Melting Point | 130-136ºC | |
| MSDS | USA | Flash Point | 301.5±26.6 °C | |
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Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells.
Mol. Pharmacol. 87(3) , 513-24, (2015) Iron is an essential cellular nutrient, being a critical cofactor of several proteins involved in cell growth and replication. Compared with normal cells, neoplastic cells have been shown to require a greater amount of iron, thus laying the basis for the prom... |
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ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel d-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58.
J. Biol. Chem. 290 , 28963-76, (2015) Innovations in the discovery of the functions of uncharacterized proteins/enzymes have become increasingly important as advances in sequencing technology flood protein databases with an exponentially growing number of open reading frames. This study documents... |
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Bacterial L-arabinose isomerases: industrial application for D-tagatose production.
Recent Pat. DNA Gene Seq. 5(3) , 194-201, (2011) D-tagatose is a natural monosaccharide with a low caloric value and has an anti-hyperglycemiant effect. This hexose has potential applications both in pharmaceutical and agro-food industries. However, the use of D-tagatose remains limited by its production co... |
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Creation of metal-independent hyperthermophilic L-arabinose isomerase by homologous recombination.
J. Agric. Food Chem. 59 , 12939-12947, (2011) Hyperthermophilic L-arabinose isomerases (AIs) are useful in the commercial production of D-tagatose as a low-calorie bulk sweetener. Their catalysis and thermostability are highly dependent on metals, which is a major drawback in food applications. To study ... |
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Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans.
Am. J. Clin. Nutr. 95(1) , 78-83, (2012) Macronutrient "preloads" can stimulate glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), slow gastric emptying, and reduce postprandial glycemic excursions. After sweet preloads, these effects may be signaled by sodium-gl... |
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Production of D-tagatose, a low caloric sweetener during milk fermentation using L-arabinose isomerase.
Bioresour. Technol. 102 , 3309-3315, (2011) Lactobacillusdelbrueckii subsp. bulgaricus and Streptococcus thermophilus are used for the biotransformation of milk in yoghurt. During milk fermentation, these lactic acid bacteria (LAB) hydrolyze lactose producing a glucose moiety that is further metabolize... |
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The acid-tolerant L-arabinose isomerase from the mesophilic Shewanella sp. ANA-3 is highly active at low temperatures.
Microb. Cell Fact. 10 , 96, (2011) L-arabinose isomerases catalyse the isomerization of L-arabinose into L-ribulose at insight biological systems. At industrial scale of this enzyme is used for the bioconversion of D-galactose into D-tagatose which has many applications in pharmaceutical and a... |
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Synthesis and Physicochemical Characterization of D-Tagatose-1-Phosphate: The Substrate of the Tagatose-1-Phosphate Kinase in the Phosphotransferase System-Mediated D-Tagatose Catabolic Pathway of Bacillus licheniformis.
J. Mol. Microbiol. Biotechnol. 25 , 106-19, (2015) We report the first enzymatic synthesis of D-tagatose-1-phosphate (Tag-1P) by the multicomponent phosphoenolpyruvate:sugar phosphotransferase system (PEP-PTS) present in tagatose-grown cells of Klebsiella pneumoniae. Physicochemical characterization by (31)P ... |
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Sensory characteristics and relative sweetness of tagatose and other sweeteners.
J. Food Sci. 77(9) , S323-8, (2012) The present study investigated the sensory characteristics and relative sweetness of tagatose, an emerging natural low-calorie sweetener with various functional properties, compared to other sweeteners (sucrose, sucralose, erythritol, rebaudioside A), over a ... |
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Tagatose: from a sweetener to a new diabetic medication?
Expert Opin. Investig. Drugs 19(2) , 285-94, (2010) Tagatose is a naturally occurring simple sugar that is a more palatable bulk low-calorie (1.5 kcal/g) sweetener. It was approved as a food additive by the FDA in 2003. Tagatose has been studied as a potential antidiabetic and antiobesity medication. In prelim... |