Sodium chenodeoxycholate

Sodium chenodeoxycholate Structure
Sodium chenodeoxycholate structure
Common Name Sodium chenodeoxycholate
CAS Number 2646-38-0 Molecular Weight 414.55
Density N/A Boiling Point 547.1ºC at 760mmHg
Molecular Formula C24H39NaO4 Melting Point 298 °C(dec.)
MSDS Chinese USA Flash Point 298.8ºC
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

Bile acids repress hypoxia-inducible factor 1 signaling and modulate the airway immune response.

Infect. Immun. 82(9) , 3531-41, (2014)

Gastroesophageal reflux (GER) frequently occurs in patients with respiratory disease and is particularly prevalent in patients with cystic fibrosis. GER is a condition in which the duodenogastric contents of the stomach leak into the esophagus, in many cases ...

Chenodeoxycholate in females with irritable bowel syndrome-constipation: a pharmacodynamic and pharmacogenetic analysis.

Gastroenterology 139 , 1549, (2010)

Sodium chenodeoxycholate (CDC) accelerates colonic transit in health. Our aim was to examine pharmacodynamics (colonic transit, bowel function) and pharmacogenetics of CDC in constipation-predominant irritable bowel syndrome (IBS-C).In a double-blind placebo-...

Bile salt/acid induction of DNA damage in bacterial and mammalian cells: implications for colon cancer.

Nutr. Cancer 16 , (1991)

Two bile salts, sodium chenodeoxycholate and sodium deoxycholate, induced a DNA repair response in the bacterium Escherichia coli. Similarly, a bile acid and a bile salt, chenodeoxycholic acid and sodium deoxycholate, induced DNA repair (indicated by unschedu...

Physical and chemical factors influencing the germination of Clostridium difficile spores.

J. Appl. Microbiol. 105 , 2223, (2008)

To investigate the influence of chemical and physical factors on the rate and extent of germination of Clostridium difficile spores.Germination of C. difficile spores following exposure to chemical and physical germinants was measured by loss of either heat o...