Pentobarbital
Pentobarbital structure
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Common Name | Pentobarbital | ||
|---|---|---|---|---|
| CAS Number | 76-74-4 | Molecular Weight | 226.27200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H18N2O3 | Melting Point | 129.5°C | |
| MSDS | N/A | Flash Point | 48.2 °F | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
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The slow death of lethal injection.
BMJ 348 , g2670, (2014)
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Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice.
Life Sci. 95(1) , 1-8, (2014) Aldehyde reductase (AKR1A), a member of the aldo-keto reductase superfamily, is highly expressed in the liver and is involved in both the detoxification of carbonyl compounds and ascorbic acid biosynthesis. By comparison with wild-type mice, Akr1a-knockout (A... |
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Optimized administration regimen of lopinavir for a myocardial ischaemia reperfusion study in Sprague-Dawley rats.
Lab. Anim. 47(2) , 122-6, (2013) Pharmacokinetics of drugs may differ between small and large mammals (including humans); therefore, drug testing in animal models must be carefully designed. Sprague-Dawley rats were used in cardiac experiments, during which the lopinavir concentration in ser... |
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Hemodiafiltration in pentobarbital poisoning.
Ren. Fail. 18(2) , 299-303, (1996) We report the use of continuous venovenous hemodiafiltration (CVVHD) in a case of massive intentional ingestion of pentobarbital associated with severe coma and hypotension. Despite a poor hemodynamic state, toxic epuration (15% of drug ingested) was obtained... |
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Impairment of an electroconvulsive stimulus on reconsolidation of memories established by conditioning.
Chin. J. Physiol. 56(1) , 44-51, (2013) The deduced memory consolidation and reconsolidation phases are sensitive to similar amnesic and memory-enhancing treatment. Electroconvulsive stimulus has been well known to impair memory consolidation. Therefore, we hypothesized that electroconvulsive stimu... |
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Sedative and hypnotic effect of freeze-dried paeoniflorin and sini san freeze-dried powder in pentobarbital sodium-induced mice.
J. Tradit. Chin. Med. 34(2) , 184-7, (2014) To investigate the sedative and hypnotic activity of paeoniflorin and freeze-dried Sini San powder on mice and provide a reliable method for determining the pharmacodynamic material basis of Sini San.Male adult mice weighing 20-22 g were used in this study. T... |
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Pentobarbital withdrawal and treatment in an infant in the pediatric cardiac intensive care unit.
J. Clin. Anesth. 25(1) , 62-5, (2013) Withdrawal syndromes following administration of sedative and analgesic infusions represent a significant morbidity that is described increasingly in the pediatric critical care literature. However, there are few descriptions of pentobarbital withdrawal sympt... |
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Pentobarbital for refractory intracranial hypertension: time to "go retro"?
Pediatr. Crit. Care Med. 14(3) , 323-4, (2013)
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WMA says doctors must not prescribe drugs for execution.
BMJ 345 , e7076, (2012)
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Midazolam and pentobarbital for refractory status epilepticus.
Pediatr. Neurol. 20(4) , 259-64, (1999) Status epilepticus, a serious, life-threatening emergency characterized by prolonged seizure activity, occurs most commonly in pediatric patients. Although initial therapies with agents such as diazepam, phenytoin, or phenobarbital generally terminate seizure... |