Renal Failure 1996-03-01

Hemodiafiltration in pentobarbital poisoning.

E Bironneau, F Garrec, M F Kergueris, A Testa, F Nicolas

Index: Ren. Fail. 18(2) , 299-303, (1996)

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Abstract

We report the use of continuous venovenous hemodiafiltration (CVVHD) in a case of massive intentional ingestion of pentobarbital associated with severe coma and hypotension. Despite a poor hemodynamic state, toxic epuration (15% of drug ingested) was obtained. However, death occurred 7 hr after the end of treatment. This report suggests that CVVHD can be effective in the treatment of massive pentobarbital intoxication.