AIDA
AIDA structure
|
Common Name | AIDA | ||
|---|---|---|---|---|
| CAS Number | 168560-79-0 | Molecular Weight | 221.20900 | |
| Density | 1.481 g/cm3 | Boiling Point | 470.4ºC at 760 mmHg | |
| Molecular Formula | C11H11NO4 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 238.3ºC | |
|
Bordetella pertussis Adenylate Cyclase Toxin Blocks Induction of Bactericidal Nitric Oxide in Macrophages through cAMP-Dependent Activation of the SHP-1 Phosphatase.
J. Immunol. 194 , 4901-13, (2015) The adenylate cyclase toxin-hemolysin (CyaA) plays a key role in the virulence of Bordetella pertussis. CyaA penetrates complement receptor 3-expressing phagocytes and catalyzes uncontrolled conversion of cytosolic ATP to the key second messenger molecule cAM... |
|
|
Cross talk between ABC transporter mRNAs via a target mRNA-derived sponge of the GcvB small RNA.
EMBO J. 34 , 1478-92, (2015) There is an expanding list of examples by which one mRNA can posttranscriptionally influence the expression of others. This can involve RNA sponges that sequester regulatory RNAs of mRNAs in the same regulon, but the underlying molecular mechanism of such mRN... |
|
|
In vivo evaluation of porous silicon and porous silicon solid lipid nanocomposites for passive targeting and imaging.
Mol. Pharm. 11(8) , 2876-86, (2014) The use of nanoparticle carriers for the sustained release of cytotoxic drugs in cancer therapy can result in fewer adverse effects and can thus be of great benefit for the patient. Recently, a novel nanocomposite, prepared by the encapsulation of THCPSi nano... |
|
|
Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damage.
J. Clin. Invest. 124(8) , 3645-55, (2014) During brain ischemia, an excessive release of glutamate triggers neuronal death through the overactivation of NMDA receptors (NMDARs); however, the underlying pathways that alter glutamate homeostasis and whether synaptic or extrasynaptic sites are responsib... |
|
|
mGluR5 protect astrocytes from ischemic damage in postnatal CNS white matter.
Cell Calcium 58 , 423-30, (2015) Astrocytes perform essential neuron-supporting functions in the central nervous system (CNS) and their disruption has devastating effects on neuronal integrity in multiple neuropathologies. Although astrocytes are considered resistant to most pathological ins... |
|
|
Unbiased transcriptional comparisons of generalist and specialist herbivores feeding on progressively defenseless Nicotiana attenuata plants.
PLoS ONE 5 , e8735, (2010) Herbivore feeding elicits dramatic increases in defenses, most of which require jasmonate (JA) signaling, and against which specialist herbivores are thought to be better adapted than generalist herbivores. Unbiased transcriptional analyses of how neonate lar... |
|
|
Generation of covalently closed circular DNA of hepatitis B viruses via intracellular recycling is regulated in a virus specific manner.
PLoS Pathog. 6 , e1001082, (2010) Persistence of hepatitis B virus (HBV) infection requires covalently closed circular (ccc)DNA formation and amplification, which can occur via intracellular recycling of the viral polymerase-linked relaxed circular (rc) DNA genomes present in virions. Here we... |
|
|
Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.
J. Cell Biol. 179 , 1453-66, (2008) Bcl-2 family member Bid is subject to autoinhibition; in the absence of stimuli, its N-terminal region sequesters the proapoptotic Bcl-2 homology 3 (BH3) domain. Upon proteolytic cleavage in its unstructured loop, Bid is activated, although structural data re... |
|
|
Temporal dynamics of a homeostatic pathway controlling neural network activity.
Front. Mol. Neurosci. 6 , 28, (2013) Neurons use a variety of mechanisms to homeostatically regulate neural network activity in order to maintain firing in a bounded range. One such process involves the bi-directional modulation of excitatory synaptic drive in response to chronic changes in netw... |
|
|
Relationship Between Infarct Size and Outcomes Following Primary PCI: Patient-Level Analysis From 10 Randomized Trials.
J. Am. Coll. Cardiol. 67 , 1674-83, (2016) Prompt reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) reduces infarct size and improves survival. However, the intuitive link between infarct size and prognosis has not been convincingly demonstrated in the contemporary era.Th... |