Paroxetine maleate
Paroxetine maleate structure
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Common Name | Paroxetine maleate | ||
|---|---|---|---|---|
| CAS Number | 64006-44-6 | Molecular Weight | 445.44 | |
| Density | 1.213 g/cm3 | Boiling Point | 451.7ºC at 760 mmHg | |
| Molecular Formula | C23H24FNO7 | Melting Point | 136-138ºC | |
| MSDS | Chinese USA | Flash Point | 227ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A thorough QTc study of 3 doses of iloperidone including metabolic inhibition via CYP2D6 and/or CYP3A4 and a comparison to quetiapine and ziprasidone.
J. Clin. Psychopharmacol. 33(1) , 3-10, (2013) The potential for iloperidone, a D2/5-HT2A antipsychotic, to affect the heart rate-corrected QT interval (QTc) was assessed in the absence and presence of metabolic inhibitors in a randomized, open-label, multicenter study. QT interval prolongation by medicat... |
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Chronic angle-closure glaucoma related to paroxetine treatment.
Semin. Ophthalmol. 28(4) , 244-6, (2013) To present a unique case of a 33-year-old woman using paroxetine who presented with acute unilateral visual loss due to chronic angle-closure glaucoma.Case report.A 33-year-old women who had been under paroxetine treatment for the past four months presented a... |
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Paroxetine (Brisdelle) for hot flashes.
Med. Lett. Drugs Ther. 55(1428) , 85-6, (2013)
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FDA Approval of Paroxetine for Menopausal Hot Flushes
N. Engl. J. Med. 370(19) , 1777-9, (2014) An FDA advisory committee recommended against approving paroxetine for menopausal vasomotor symptoms. But recognizing the lack of hormone-free products for this indication, and after reviewing the drug's efficacy and safety, the FDA decided it can benefit som... |
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Serotonin and yawning: a potential adverse drug reaction during antidepressant therapy
Presse Med. 43(10 Pt 1) , 1135-6, (2014)
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Paroxetine approval.
Am. J. Nurs. 114(1) , 10, (2014)
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Putting GlaxoSmithKline to the test over paroxetine.
BMJ 347 , f6754, (2013)
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Paroxetine hydrochloride: polymorphs and solvatomorphs.
Profiles Drug Subst. Excip. Relat. Methodol. 38 , 407-21, (2013) The polymorphic (crystal systems for which a substance can exist in structures defined by different unit cells, and where each of the forms has the same elemental composition) and solvatomorphic (systems where the crystal structures of the substance are defin... |
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Paroxetine hydrochloride.
Profiles Drug Subst. Excip. Relat. Methodol. 38 , 367-406, (2013) Paroxetine hydrochloride (3S-trans)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-piperidine hydrochloride (or (-)-(3S,4R)-(4-(p-fluorophenyl)-3-[[3,4-(methylenedioxy)-phenoxy]methyl]piperidine hydrochloride), a phenylpiperidine derivative, is a sele... |
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GSK paid smaller companies to delay generic versions of paroxetine, says fair trade body.
BMJ 346 , f2566, (2013)
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