Mycophenolate mofetil
Mycophenolate mofetil structure
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Common Name | Mycophenolate mofetil | ||
|---|---|---|---|---|
| CAS Number | 128794-94-5 | Molecular Weight | 433.495 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 637.6±55.0 °C at 760 mmHg | |
| Molecular Formula | C23H31NO7 | Melting Point | 95-96ºC | |
| MSDS | Chinese USA | Flash Point | 339.4±31.5 °C | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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Safety and efficacy of the early introduction of everolimus with reduced-exposure cyclosporine a in de novo kidney recipients.
Transplantation 99(1) , 180-6, (2015) Everolimus and cyclosporine A (CsA) exhibit synergistic immunosuppressive activity when used in combination. We examined the safety and efficacy of the use of everolimus with a cyclosporine-sparing strategy in de novo renal transplant recipients.A comparative... |
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Preemptive thoracic drainage to eradicate postoperative pulmonary complications after living donor liver transplantation.
J. Am. Coll. Surg. 219(6) , 1134-42.e2, (2014) Thoracic fluid retention after living donor liver transplantation (LDLT) has various negative consequences, including atelectasis, pneumonia, and respiratory distress or failure.We analyzed the clinical impact of preemptive thoracic drainage in 177 patients u... |
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The risk of recurrent IgA nephropathy in a steroid-free protocol and other modifying immunosuppression.
Clin. Transplant. 28(8) , 845-54, (2014) Recurrent glomerulonephritis is an important cause of kidney allograft failure. The effect of immunosuppression on recurrent IgA nephropathy (IgAN) is unclear. We analyzed the impact of steroids and other immunosuppression on the risk of recurrent IgAN post-k... |
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Successful treatment of severe myasthenia gravis developed after allogeneic hematopoietic stem cell transplantation with plasma exchange and rituximab.
Pediatr. Blood Cancer 61(5) , 928-30, (2014) Myasthenia gravis is among the rare complications after allogeneic hematopoietic stem cell transplantation and is usually associated with chronic GVHD. Herein, we report a 2-year and 10 months of age female with Griscelli syndrome, who developed severe myasth... |
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Cytomegalovirus retinitis: a rare but preventable cause of blindness in dermatology patients.
J. Cutan. Med. Surg. 18(4) , 287-90, (2014) Dermatologists are using an increasing range of immunomodulatory therapies to treat an expanding number of skin diseases. Complications of therapy are broad and include infection. Cytomegalovirus (CMV) retinitis has not been reported in association with derma... |
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Cyclosporine in combination with mycophenolate mofetil versus methotrexate for graft versus host disease prevention in myeloablative HLA-identical sibling donor allogeneic hematopoietic cell transplantation.
Am. J. Hematol. 90(2) , 144-8, (2015) Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality in allogeneic hematopoietic cell transplantation (HCT) despite current prophylaxis. Methotrexate (MTX) with a calcineurin inhibitor (CNI) is the current standard, however, has s... |
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Alloimmune responses and atherosclerotic disease after kidney transplantation.
Transplantation 99(1) , 220-5, (2014) Chronic exposure to exogenous antigens causes accumulation of proinflammatory CD57(+)CD28(-) hyperactivated CD8(+) T cells that may promote atherosclerosis. We hypothesized that persistent alloimmune responses may induce immune activation and contribute to po... |
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Effect of N-acetylcysteine pretreatment of deceased organ donors on renal allograft function: a randomized controlled trial.
Transplantation 99(4) , 746-53, (2015) Antioxidant donor pretreatment is one of the pharmacologic strategy proposed to prevent renal ischemia-reperfusion injuries and delayed graft function (DGF). The aim of the study was to investigate whether a donor pretreatment with N-acetylcysteine (NAC) redu... |
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Success with single-agent immunosuppression for multifocal choroidopathies.
Am. J. Ophthalmol. 158(6) , 1310-7, (2014) To evaluate the success of single-agent immunosuppression for patients with the posterior uveitides, birdshot chorioretinitis, multifocal choroiditis with panuveitis, and punctate inner choroiditis.Retrospective case series.setting: Tertiary care uveitis prac... |
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Generation of suppressive blood cells for control of allograft rejection.
Clin. Sci. 128(9) , 593-607, (2015) Our previous studies in rats showed that incubation of monocytic dendritic cells (DCs) with the chemotherapeutic drug mitomycin C (MMC) renders the cells immunosuppressive. Donor-derived MMC-DCs injected into the recipient prior to transplantation prolonged h... |