2-aminofluorene
2-aminofluorene structure
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Common Name | 2-aminofluorene | ||
|---|---|---|---|---|
| CAS Number | 153-78-6 | Molecular Weight | 181.233 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 379.3±21.0 °C at 760 mmHg | |
| Molecular Formula | C13H11N | Melting Point | 124-128 °C(lit.) | |
| MSDS | USA | Flash Point | 204.8±17.4 °C | |
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Safety and mutagenicity evaluation of Vigiis 101 powder made from Lactobacillus paracasei subsp. paracasei NTU 101.
Regul Toxicol Pharmacol 71(2) , 148-57, (2015) The aim of the present work was to assess the genotoxic activity and the potential for toxicity upon repeated dosing of "Vigiis 101" powder, a probiotic consisting of dried bacteria Lactobacillus paracasei subsp. paracasei NTU 101. Results of the Ames test in... |
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Safety assessment of dietary bamboo charcoal powder: a 90-day subchronic oral toxicity and mutagenicity studies.
Food Chem. Toxicol. 75 , 50-7, (2015) Vegetable carbon has been used as food additive in EU (E153) and China for many years; however, no experimental data have been available on its dietary safety. This study was designed to evaluate the subchronic toxicity and genotoxicity of bamboo charcoal pow... |
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Phytotoxicity and genotoxicity assessment of imazethapyr herbicide using a battery of bioassays.
Environ. Sci. Pollut. Res. Int. 22 , 19194-202, (2015) The imazethapyr herbicide (formulation Verosil(®)) was evaluated for phytotoxicity and genotoxicity using a battery of bioassays: (1) the growth inhibition of the green alga Pseudokirchneriella subcapitata, (2) the root growth and germination of the higher pl... |
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Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines.
Eur. J. Med. Chem. 42 , 1396-402, (2007) Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry and their mutagenic capacity. Biopartitioning micellar chr... |
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Safety evaluation of a triazine compound nitromezuril by assessing bacterial reverse mutation, sperm abnormalities, micronucleus and chromosomal aberration.
Regul Toxicol Pharmacol 71(3) , 585-9, (2015) Nitromezuril (NZL) is a novel triazine compound that exhibits remarkable anticoccidial activity. However, mutagenicity and genotoxicity of NZL have not been evaluated to date. This study evaluated the potential risks of NZL by testing for bacterial reverse mu... |
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The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat.
Exp. Mol. Pathol. 93(1) , 40-9, (2012) Oval cell activation occurs under conditions of severe liver injury when normal hepatocyte proliferation is blocked. Recent studies have shown that a subset of hepatocellular carcinomas expresses oval cell markers, suggesting that these cells are targets of h... |
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Cellular proliferation, cell death, and liver histology in Gambusia affinis after dietary exposure to benzidine and 2-aminofluorene.
Int. J. Toxicol. 29(3) , 247-58, (2010) Chronic exposure to arylamines through diet and/or smoking has been associated with genetic changes and tumorigenesis. Cellular proliferation, apoptosis, and histological changes in liver tissue were investigated in Gambusia affinis (G affinis) after chronic ... |
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Screening for reactive metabolites using electro-optical arrays featuring human liver cytosol and microsomal enzyme sources and DNA.
Chem. Commun. (Camb.) (36) , 5386-8, (2009) We demonstrate for the first time the combination of human liver cytosol and microsomal enzyme sources into an electro-optical array to screen for reactive metabolites produced in multi-enzyme metabolic processes. |
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Binary and ternary binding affinities between exonuclease-deficient Klenow fragment (Kf-exo(-)) and various arylamine DNA lesions characterized by surface plasmon resonance.
Chem. Res. Toxicol. 25(8) , 1568-70, (2012) We used surface plasmon resonance (SPR) to characterize the binding interactions between the exonulease-free Klenow fragment (Kf-exo(-)) and unmodified and modified dG adducts derived from arylamine carcinogens: fluorinated 2-aminofluorene (FAF), 2-acetylamin... |
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Determination of genotoxic, antigenotoxic and cytotoxic potential of the extract from lichen Cetraria aculeata (Schreb.) Fr. in vitro.
Phytother Res. 22(1) , 118-23, (2008) Naturally occurring compounds can have protective effects towards mutagens and carcinogens as shown by numerous studies. In the present study, the genotoxic/antigenotoxic activities of the extract from lichen Cetraria aculeata (Schreb.) Fr., which has been id... |