3-CHLORO-7-HYDROXY-4-METHYLCOUMARIN
3-CHLORO-7-HYDROXY-4-METHYLCOUMARIN structure
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Common Name | 3-CHLORO-7-HYDROXY-4-METHYLCOUMARIN | ||
|---|---|---|---|---|
| CAS Number | 6174-86-3 | Molecular Weight | 210.614 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 405.8±45.0 °C at 760 mmHg | |
| Molecular Formula | C10H7ClO3 | Melting Point | 240-244 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 199.2±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Evaluation of coumaphos exposure among tick eradication workers.
J. Occup. Environ. Med. 52(2) , 131-6, (2010) To evaluate both the cholinesterase monitoring program and newer field methods of determining coumaphos exposure among tick eradication workers.Measured blood cholinesterase by the Ellman and field testing methods and tested urine for chlorferon pre- and post... |
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Biodegradation of coumaphos, chlorferon, and diethylthiophosphate using bacteria immobilized in Ca-alginate gel beads.
Bioresour. Technol. 100(3) , 1138-42, (2009) Calcium-alginate immobilized cell systems were developed for the detoxification and biodegradation of coumaphos, an organophosphate insecticide, and its hydrolysis products, chlorferon and diethlythiophosphate (DETP). Optimum bead loadings for bioreactor oper... |
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Management of the diffusion of 4-methylumbelliferone across phases in microdroplet-based systems for in vitro protein evolution.
Electrophoresis 31(18) , 3121-8, (2010) Fluorongenic reagents based on 4-methylumbelliferone (4-MU) have been widely used for the detection of phosphatase, sulfatase, esterase, lipase and glycosidase activities in conventionally formatted enzyme assay systems. However, the sensitivity of assays bas... |
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Determination of diffusion coefficients and diffusion characteristics for chlorferon and diethylthiophosphate in Ca-alginate gel beads.
Biotechnol. Bioeng. 100(4) , 698-706, (2008) Diffusion characteristics of chlorferon and diethylthiophosphate (DETP) in Ca-alginate gel beads were studied to assist in designing and operating bioreactor systems. Diffusion coefficients for chlorferon and DETP in Ca-alginate gel beads determined at condit... |
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Studies on 3-chloro-4-methyl-(4-14C)-7-hydroxycoumarin in rats.
Adv. Exp. Med. Biol. 136 Pt A , 839-46, (1981) The distribution, excretion and biotransformation of 3-chloro-4-methyl-(4-14C)-7-hydroxycoumarin [(14C) chlorferron] were studied in the rats after single oral administration. Male and female Wistar rats were given single oral doses of 0.5 and 20.0 mg/kg body... |
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Biodegradation of chlorferon and diethylthiophosphate by consortia enriched from waste cattle dip solution.
Bioresour. Technol. 98(10) , 1916-23, (2007) Chlorferon and diethylthiophosphate (DETP) are the hydrolysis products of coumaphos, an organophosphate pesticide. In this research, two consortia of bacterial cultures, one responsible for degrading chlorferon and the other for degrading DETP, were selective... |
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Reversible inhibition of acetylcholinesterase and butyrylcholinesterase by 4,4'-bipyridine and by a coumarin derivative.
Chem. Biol. Interact. 119-120 , 119-28, (1999) Inhibition of recombinant mouse wild type AChE (EC 3.1.1.7) and BChE (EC 3.1.1.8), and AChE peripheral site-directed mutants and human serum BChE variants by 4,4'-bipyridine (4,4'-BP) and the coumarin derivative 3-chloro-7-hydroxy-4-methylcoumarin (CHMC) was ... |
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Biotransformation and disposition of the coumaphos metabolite 3-chloro-4-methyl-(4-14C)-7-hydroxycoumarin in rats.
Arch. Toxicol. 48(1) , 51-9, (1981) The biotransformation and disposition of 3-chloro-4-methyl-(4-14C)-7-hydroxycoumarin [(14C) chlorferron] were investigated in rats after single oral administration. Following administration of (14C) chlorferron at 0.5 and 20 mg/kg body weight to male rats, gr... |
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Development of a simple and sensitive fluorimetric method for isolation of coumaphos-hydrolysing bacteria.
Lett. Appl. Microbiol. 34(4) , 263-8, (2002) To develop a simple, rapid and sensitive fluorimetric assay to detect, isolate and characterize a soil bacterium capable of degrading the organophosphorus pesticide, coumaphos.A high throughput microtitre plate-based method was used to quantify coumaphos hydr... |
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Elimination pattern and biodistribution of [14C]chlorferron in rats.
Toxicol. Lett. 7(6) , 449-52, (1981) Administration of [14C]chlorferron in a single oral dose of 0.5 and 20 mg/kg body weight to female rats resulted in a urinary excretion of greater than 74% of the given dose during the first 24 h. Approx. 8% of the dose was eliminated in faeces within 7 days.... |