trans-1,4-Dichlorobutene
trans-1,4-Dichlorobutene structure
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Common Name | trans-1,4-Dichlorobutene | ||
|---|---|---|---|---|
| CAS Number | 110-57-6 | Molecular Weight | 124.996 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 155.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C4H6Cl2 | Melting Point | 1-3ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 54.4±0.0 °C | |
| Symbol |
GHS02, GHS05, GHS06 |
Signal Word | Danger | |
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Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.
Bioorg. Med. Chem. 16 , 5720-32, (2008) The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper describes a QSAR model to predict direct mutagenicity for these... |
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Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.
J. Med. Chem. 30(2) , 437-40, (1987) Alkylation of adenine (5a) or 2-amino-6-chloropurine (5b) with excess trans-1,4-dichloro-2-butene (4), effected by K2CO3 in dimethyl sulfoxide or tetra-n-butylammonium fluoride in tetrahydrofuran, led in 90-95% regioselectivity to 9-alkylpurines 6a and 6b. Th... |
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Effect of isomers of swainsonine on glycosidase activity and glycoprotein processing.
Biochemistry 26(9) , 2502-10, (1987) The chemical synthesis of swainsonine [(1S,2R,8R,8 alpha R)-trihydroxyindolizidine] from trans-1,4-dichloro-2-butene was previously described [Adams, C. E., Walker, F. J., & Sharpless, K. B. (1985) J. Org. Chem. 50, 420-424]. A modification of that synthesis ... |
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Total synthesis of gigantetrocin A.
Chirality 12(7) , 581-9, (2000) A highly efficient synthetic method for the trans-tetrahydrofuran (THF) ring building block was established and the title compound was synthesized in 19 steps from trans-1,4-dichloro-2-butene via a convergent route with a Wittig reaction as the key step.Copyr... |
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[Experimental data on a hygienic standard for 1,4-dichlorobutene-2 in the air of a work area].
Gig. Tr. Prof. Zabol. (4) , 49-50, (1985)
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[Nephrotoxic action of dichlorobutenes].
Gig. Tr. Prof. Zabol. (3) , 44-5, (1985)
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[Experimental establishment of the maximum permissible concentration of 1,4- and 3,4-dichlorobutenes in reservoir water].
Gig. Sanit. (7) , 77-8, (1986)
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Allenic derivatives of nucleic acid components and their transformation products: a new class of biologically active nucleoside analogues.
Nucleic Acids Symp. Ser. (18) , 25-8, (1987) Reaction of adenine (1a) or cytosine (1b) with excess 1,4-dichloro-2-butyne catalyzed by K2CO3 in (CH3)2SO gave the 4-chloro-2-butynyl derivatives 2a and 2b. The latter were converted to the 4-hydroxy-2-butynyl compounds 3a and 3b by refluxing in 0.1 M HCl. I... |
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[The gas chromatographic determination of dichlorobutenes and trichlorobutenes in washings from the skin].
Gig. Tr. Prof. Zabol. (7) , 32-4, (1992) A sensitive selective method of unsaturated chlorated hydrocarbons detection by means of gas chromatography in skin was worked out. The limits are: for 3,4-dichlorobutene (DCB)-1-0.0024 mu g, for 1,3 DCB-2-0.0027 mu g, for 1,4-DCB-2 (cys)-0.0024 mu g, for 1,4... |
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trans-1,4-dichlorobutene.
IARC Monogr. Eval. Carcinog. Risks Hum. 71 Pt 3 , 1389-91, (1999)
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