2',3'-o-isopropylideneuridine
2',3'-o-isopropylideneuridine structure
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Common Name | 2',3'-o-isopropylideneuridine | ||
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| CAS Number | 362-43-6 | Molecular Weight | 284.26500 | |
| Density | 1.376g/cm3 | Boiling Point | 426.76°C (rough estimate) | |
| Molecular Formula | C12H16N2O6 | Melting Point | 163-166ºC | |
| MSDS | USA | Flash Point | N/A | |
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5'-Uridyl derivatives of N-glycosyl allophanic acid and biuret.
Carbohydr. Res. 345 , 163-167, (2010) (2',3'-O-Isopropylidene-5'-uridyl) 4-(2,3,4,6-tetra-O-acetyl-beta-d-glycopyranosyl)allophanates were obtained in the reactions of 2',3'-O-isopropylidene-uridine and O-peracetylated beta-d-gluco-, galacto- and xylopyranosylamines, and OCNCOCl. 2,3,4,6-Tetra-O-... |
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New methods for the synthesis of N-benzoylated uridine and thymidine derivatives; a convenient method for N-debenzoylation.
Carbohydr. Res. 337 , 369-372, (2002) An improved procedure for the synthesis of N-benzoyl-2',3'-O-isopropylidene uridine via one-step selective N-benzoylation of 2',3' -O-isopropylidene uridine has been developed. An efficient synthetic route to N-benzoyl thymidine via initial tribenzoylation, f... |
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Synthesis and central nervous system depressant effects of N3-substituted 2',3'-O-isopropylideneuridines.
Chem. Pharm. Bull. 47 , 1802-1804, (1999) N3-Substituted derivatives of 2',3'-O-isopropylideneuridine (1) were synthesized and their pharmacological effects on the central nervous system (CNS) examined using mice. Methyl (2), ethyl (3), propyl (4), butyl (5), allyl (6), benzyl (7), o-, m-, p-xylyls (... |
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Synthesis of N3-substituted uridine and related pyrimidine nucleosides and their antinociceptive effects in mice.
Chem. Pharm. Bull. 53 , 313-318, (2005) Seventy eight N(3)-substituted derivatives of uridine (1), thymidine (2), 2'-deoxyuridine (3), 6-azauridine (4), 2',3'-O-isopropylideneuridine (5), and arabinofuranosyluracil (6) were synthesized and their antinociceptive effects were evaluated. N(3)-(2',4'-D... |
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Enhancement of radiation-induced base release from nucleosides in alkaline solution: essential role of the O.- radical.
Int. J. Radiat. Biol. 61(4) , 443-9, (1992) The effect of pH on base release in the gamma-radiolysis of N2O-saturated solutions of a number of nucleosides (including uridine, 3-methyluridine, 2',3'-O-isopropylidene-uridine, and adenosine) has been investigated. For all these nucleotides, independent of... |
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[New nucleoside conjugates with phospholipids: synthesis of anti-HIV activity of rac-1-hexadecyl-2-acyl-sn-glycero-3-phosphonucleosides].
Bioorg. Khim. 23(8) , 648-54, (1997) New nucleoside-phospholipid conjugates were synthesized based on 1,2-disubstituted glycerides and nucleosides. These contain rac-1-hexadecyl-2-palmitoyl(or 2-methylcarbamoyl)-sn-glycero-3-phosphate as the phospholipid component and 2',3'-didehydro-3'-deoxythy... |