1-Naphthylacetonitrile

1-Naphthylacetonitrile Structure
1-Naphthylacetonitrile structure
Common Name 1-Naphthylacetonitrile
CAS Number 7498-57-9 Molecular Weight 167.207
Density 1.1±0.1 g/cm3 Boiling Point 323.9±0.0 °C at 760 mmHg
Molecular Formula C12H9N Melting Point 82-84 °C(lit.)
MSDS Chinese USA Flash Point 180.3±5.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Three-component coupling using arynes and DMF: straightforward access to coumarins via ortho-quinone methides.

Chem. Commun. (Camb.) 47(30) , 8512-4, (2011)

ortho-Quinone methides, arising from a formal [2+2] cycloaddition between arynes and DMF, were found to facilely undergo a [4+2] cycloaddition with ester enolates or ketenimine anions to produce diverse coumarins in a straightforward manner.This journal is © ...

Synthesis and structure-activity relationships of 2-alkylidenethiazolidine-4,5-diones as antibiotic agents.

Bioorg. Med. Chem. 13(14) , 4402-7, (2005)

2-Alkylidenethiazolidine-4,5-diones were prepared by novel one-pot cyclizations of arylacetonitriles with isothiocyanates and ethyl 2-chloro-2-oxoacetate. The products show antibiotic activity against the Gram-positive bacteria Bacillus subtilis and Staphyloc...