β-Naphthoflavone

β-Naphthoflavone Structure
β-Naphthoflavone structure
Common Name β-Naphthoflavone
CAS Number 6051-87-2 Molecular Weight 272.30
Density 1.3±0.1 g/cm3 Boiling Point 460.9±45.0 °C at 760 mmHg
Molecular Formula C19H12O2 Melting Point 185-189 °C
MSDS USA Flash Point 215.8±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Physiological response of alligator gar juveniles (Atractosteus spatula) exposed to sub-lethal doses of pollutants.

Fish Physiol. Biochem. 41 , 1015-27, (2015)

Alligator gar populations have declined because of overfishing, habitat loss and pollution. Over time, the exposure to different pollutants have affected these fishes as a consequence of their high trophic level, bottom-dwelling habits and long life span. In ...

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium.

EMBO J. 34 , 1319-35, (2015)

Snail family members regulate epithelial-to-mesenchymal transition (EMT) during invasion of intestinal tumours, but their role in normal intestinal homeostasis is unknown. Studies in breast and skin epithelia indicate that Snail proteins promote an undifferen...

Direct surface visualization of biofilms with high spin coordination clusters using Magnetic Resonance Imaging.

Acta Biomater. 31 , 167-77, (2016)

Magnetic Resonance Imaging is a powerful tool for the investigation of a biofilms' physical structure determining mass transport behavior which is of major importance in biofilm research. The entire biofilm is imaged in situ non-invasively and non-destructive...

Improved assays for xenosensor activation based on reverse transfection.

Toxicol. In Vitro 29 , 1759-65, (2015)

Discovery of receptor-dependent mechanisms for regulation of drug metabolism has provided a new way to evaluate the propensity of drug candidates to cause induction of cytochrome P450 enzymes. Therefore, receptor-based reporter assays have become common in ea...

Rapid and sensitive assessment of human hepatocyte functions.

Cell. Transplant. 23(12) , 1545-56, (2015)

Transplantation of human hepatocytes (HTx) has gained recognition as a bridge to, or an alternative to, orthotopic liver transplantation for patients with acute liver failure or genetic defects in liver function. Although the quality of the hepatocytes used f...

Preparation of pellets with controlled release of glucose as prevention of hypoglycaemia in paediatric patients.

Eur. J. Pharm. Sci. 75 , 72-80, (2015)

Hypoglycaemic episodes represent serious and frequent complications of type 1 and 2 diabetes. Theoretically, the risk of hypoglycaemic states can be affected by a dosage form based on a food supplement containing a delayed release formulation of glucose. The ...

Stage-dependent ethoxyresorufin-O-deethylase (EROD) in vivo activity in medaka (Oryzias latipes) embryos.

Chemosphere 135 , 108-15, (2015)

Using medaka (Oryzias latipes) embryos, this study aimed to quantitatively characterize the stage-dependent in vivo ethoxyresorufin-O-deethylase (EROD) as indicator of cytochrome P4501A (CYP1A) activity. Embryos were challenged for 24-h to an agonist (β-napht...

Baicalin Protects Mice from Aristolochic Acid I-Induced Kidney Injury by Induction of CYP1A through the Aromatic Hydrocarbon Receptor.

Int. J. Mol. Sci. 16 , 16454-68, (2015)

Exposure to aristolochic acid I (AAI) can lead to aristolochic acid nephropathy (AAN), Balkan endemic nephropathy (BEN) and urothelial cancer. The induction of hepatic CYP1A, especially CYP1A2, was considered to detoxify AAI so as to reduce its nephrotoxicity...

Gastro-resistant characteristics of GRAS-grade enteric coatings for pharmaceutical and nutraceutical products.

Int. J. Pharm. 486 , 167-74, (2015)

The use of naturally derived excipients to develop enteric coatings offers significant advantages over conventional synthetic polymers. Unlike synthetic polymers, they are biodegradable, relatively abundant, have no daily intake limits or restrictions on use ...

Radix Puerariae lobatae (Gegen) suppresses the anticoagulation effect of warfarin: a pharmacokinetic and pharmacodynamics study.

Chin. Med. 11 , 7, (2016)

Radix Salvia miltiorrhiza (Danshen) and Radix Puerariae lobatae (Gegen) are used in Traditional Chinese Medicine to treat cardiovascular diseases. However, adverse herb-drug interactions were observed between warfarin and herbal remedies containing Danshen an...