5-Chloro-2-Fluorotoluene

5-Chloro-2-Fluorotoluene Structure
5-Chloro-2-Fluorotoluene structure
Common Name 5-Chloro-2-Fluorotoluene
CAS Number 452-66-4 Molecular Weight 144.574
Density 1.2±0.1 g/cm3 Boiling Point 162.7±20.0 °C at 760 mmHg
Molecular Formula C7H6ClF Melting Point N/A
MSDS Chinese USA Flash Point 52.5±7.3 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

Palladium-Catalyzed C(sp(3))-C(sp(2)) Cross-Coupling of (Trimethylsilyl)methyllithium with (Hetero)Aryl Halides.

Org. Lett. , (2015)

The palladium-catalyzed direct cross-coupling of a range of organic chlorides and bromides with the bifunctional C(sp(3))-(trimethylsilyl)methyllithium reagent is reported. The use of Pd-PEPPSI-IPent as the catalyst allows for the preparation of structurally ...

Topically active carbonic anhydrase inhibitors. 4. [(Hydroxyalkyl)sulfonyl]benzene and [(hydroxyalkyl)sulfonyl]thiophenesulfonamides.

J. Med. Chem. 34 , 3098, (1991)

For several decades a tantalizing goal for the treatment of primary open-angle glaucoma has been the development of a topically active carbonic anhydrase inhibitor. Recent results from several research groups indicate that considerable progress has been made ...

Synthesis and antihypertensive activity of 1,4-dihydropyridine derivatives with a 4-(disubstituted phenyl) ring and an aminoalkyl ester group: highly potent and long-lasting calcium antagonists.

Chem. Pharm. Bull. 40 , 2049, (1992)

New 1,4-dihydropyridine derivatives bearing a 4-(disubstituted phenyl) ring and an aminoethyl ester or an amino-2,2-dimethyl-propyl ester were synthesized and their antihypertensive activities were examined in normotensive rats and spontaneously hypertensive ...