Benzylhydrazine dihydrochloride
Benzylhydrazine dihydrochloride structure
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Common Name | Benzylhydrazine dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 20570-96-1 | Molecular Weight | 195.090 | |
| Density | 1.033g/cm3 | Boiling Point | 265.4ºC at 760 mmHg | |
| Molecular Formula | C7H12Cl2N2 | Melting Point | 143-145 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 132ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Determination of hydrazine in pharmaceuticals IV: Hydrazine and benzylhydrazine in isocarboxazid.
J. Pharm. Sci. 74(1) , 105-7, (1985) A GC procedure for the simultaneous determination of hydrazine and benzylhydrazine in isocarboxazid raw material and tablet formulations has been developed. The method is based on the reaction of benzoyltrifluoroacetone with hydrazine and benzylhydrazine to f... |
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Benzylhydrazine as a pseudo-substrate of bovine serum amine oxidase.
Biochem. J. 260(1) , 19-25, (1989) Bovine serum amine oxidase is inhibited by benzylhydrazine (BHy), but recovers full activity after a few hours incubation [Hucko-Haas & Reed (1970) Biochem. Biophys. Res. Commun. 38, 396-400]. The first phase of the process, requiring about 15 min, was found ... |
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Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assay.
Bioorg. Med. Chem. 12(13) , 3649-55, (2004) A series of indole-2-carboxylic acid benzylidene-hydrazides has been identified as a new class of potent apoptosis inducers through a novel cell-based caspase HTS assay. The screening hit, 5-chloro-3-methyl-indole-2-carboxylic acid (4-nitrobenzylidene)-hydraz... |
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Selective mechanism-based inactivation of peptidylglycine alpha-hydroxylating monooxygenase in serum and heart atrium vs. brain.
Biochem. Pharmacol. 53(11) , 1695-702, (1997) Peptidylglycine alpha-hydroxylating monooxygenase (PHM; EC 1.14.17.3) catalyses the rate-limiting step in the post-translational activation of substance P, among other neuropeptides, from its glycine-extended precursor. Comparative kinetic studies were perfor... |
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The role of copper in bovine serum amine oxidase.
Biol. Met. 3(2) , 114-7, (1990) The role of copper in bovine serum amine oxidase was investigated by studying the effect of copper-binding inhibitors on the reactions of the pyrroloquinoline quinone carbonyl and on the reaction with oxygen. Hydrazines and hydrazides were used as carbonyl re... |
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Complexes of the copper-containing amine oxidase from Arthrobacter globiformis with the inhibitors benzylhydrazine and tranylcypromine.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64(Pt 7) , 577-83, (2008) Complexes of Arthrobacter globiformis amine oxidase (AGAO) with the inhibitors benzylhydrazine and tranylcypromine (an antidepressant drug) have been refined at 1.86 and 1.65 A resolution, respectively. Both inhibitors form covalent adducts with the TPQ cofac... |
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The oxidation and reduction reactions of bovine serum amine oxidase. A kinetic study.
Eur. J. Biochem. 267(11) , 3264-9, (2000) The presteady-state and steady-state kinetics of bovine serum amine oxidase (BSAO) were analyzed by stopped-flow transient spectroscopy. A simplified model of the catalytic cycle was found to describe the experimental data and the rate constants of the indivi... |
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The inactivation of bifunctional peptidylglycine alpha-amidating enzyme by benzylhydrazine: evidence that the two enzyme-bound copper atoms are nonequivalent.
Arch. Biochem. Biophys. 317(1) , 93-102, (1995) Peptidylglycine alpha-amidating enzyme catalyzes the two-step conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides and glyoxylate in a reaction that requires O2, ascorbate and 2 mol of copper per mole of enzyme [Kulathila e... |