N-butylisocyanide
N-butylisocyanide structure
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Common Name | N-butylisocyanide | ||
|---|---|---|---|---|
| CAS Number | 2769-64-4 | Molecular Weight | 83.13170 | |
| Density | 0.795 g/mL at 25 °C(lit.) | Boiling Point | N/A | |
| Molecular Formula | C5H9N | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 69 °F | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
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n-Butyl isocyanide oxidation at the [NiFe4S4OH(x)] cluster of CO dehydrogenase.
J. Biol. Inorg. Chem. 17(2) , 167-73, (2012) Carbon monoxide dehydrogenases (CODHs) catalyze the reversible oxidation of carbon monoxide by reaction with water to yield carbon dioxide, two protons, and two electrons. Two principal types of CODHs can be distinguished. Ni,Fe-containing CODHs contain a [Ni... |
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Butyl isocyanide as a probe of the activation mechanism of soluble guanylate cyclase. Investigating the role of non-heme nitric oxide.
J. Biol. Chem. 282(49) , 35741-8, (2007) Nitric oxide (NO) is a physiologically relevant activator of the hemoprotein soluble guanylate cyclase (sGC). In the presence of NO, sGC is activated several hundredfold above the basal level by a mechanism that remains to be elucidated. The heme ligand n-but... |
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Kinetics of intramolecular charge transfer with N-phenylpyrrole in alkyl cyanides.
J. Phys. Chem. A 109(8) , 1497-509, (2005) For the electron acceptor/donor molecule N-phenylpyrrole (PP), the fast intramolecular charge transfer (ICT) reaction accompanied by dual fluorescence from a locally excited (LE) and an ICT state is investigated in alkyl cyanide solvents as a function of temp... |
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Alkyl and aromatic isocyanide binding to haem complexes.
Biochem. J. 262(3) , 959-63, (1989) Equilibrium constants for the binding of ethyl (EIC), n-butyl (BIC), p-toluenesulphonylmethyl (TMIC) and 2,6-dimethylphenyl isocyanides (DIMPI) to an imidazole-haem complex in toluene and aqueous detergent micelle solutions were determined. In contrast to an ... |
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Proton nuclear magnetic resonance study of the binary complex of cytochrome P450cam and putidaredoxin: interaction and electron transfer rate analysis.
FEBS Lett. 455(3) , 302-6, (1999) A 1H nuclear magnetic resonance study of the complex of cytochrome P450cam-putidaredoxin has been performed. Isocyanide is bound to cytochrome P450cam in order to increase the stability of the protein both in the reduced and the oxidized state. Diprotein comp... |
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Distal ligand reactivity and quaternary structure studies of proximally detached hemoglobins.
Biochemistry 40(13) , 3780-95, (2001) The linkage between the proximal histidines and the proximal polypeptide in normal adult human hemoglobin (Hb A) has been proposed to play a major role in transmitting allosteric effects between oxygen binding sites [Perutz, M. F. (1970) Nature 228, 726-734].... |
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Elucidation of the differences between the 430- and 455-nm absorbing forms of P450-isocyanide adducts by resonance Raman spectroscopy.
J. Biol. Chem. 276(39) , 36261-7, (2001) Alkylisocyanide adducts of microsomal P450 exist in two interconvertible forms, each giving the Soret maximum around 430 or 455 nm. This is demonstrated with a rabbit liver P450 2B4. Resonance Raman spectra of the 430- and 455-nm forms were examined for typic... |
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Geminate recombination of n-butyl isocyanide to myoglobin.
Biochemistry 24(25) , 7380-8, (1985) Transient optical absorption spectra of myoglobin were measured following photolysis of the n-butyl isocyanide complex with 10-ns laser pulses at room temperature. The data were analyzed by using singular value decomposition to give the kinetics of ligand reb... |
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Isocyanides inhibit human heme oxygenases at the verdoheme stage.
Biochemistry 48(37) , 8920-8, (2009) Heme oxygenases (HO) catalyze the oxidative cleavage of heme to generate biliverdin, CO, and free iron. In humans, heme oxygenase-1 (hHO-1) is overexpressed in tumor tissues, where it helps to protect cancer cells from anticancer agents, while HOs in fungal p... |
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Effect of isocyanide on the ultrastructure of mouse pineal.
Anat. Histol. Embryol. 13(2) , 181-8, (1984)
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