2-di-1-asp
2-di-1-asp structure
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Common Name | 2-di-1-asp | ||
|---|---|---|---|---|
| CAS Number | 2156-29-8 | Molecular Weight | 366.24000 | |
| Density | 1.091g/cm3 | Boiling Point | 397.8℃at 760 mmHg | |
| Molecular Formula | C16H19IN2 | Melting Point | 280ºC (dec.)(lit.) | |
| MSDS | USA | Flash Point | 179.3℃ | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Proc. Natl. Acad. Sci. U. S. A. 105 , 9059-64, (2008) The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have implemented an efficient and robust high-throughput cell-based screen (1,536-well format) based on p... |
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Distribution pattern of viable mitochondria in bovine lens epithelial cells.
Dev. Ophthalmol. 26 , 90-6, (1994)
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Live-cell imaging of the cytoskeleton and mitochondrial-cytoskeletal interactions in budding yeast.
Methods Mol. Biol. 586 , 41-68, (2009) This chapter describes labeling methods and optical approaches for live-cell imaging of the cytoskeleton and of a specific organelle-cytoskeleton interaction in budding yeast. |
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Lack of mitochondrial anionic phospholipids causes an inhibition of translation of protein components of the electron transport chain. A yeast genetic model system for the study of anionic phospholipid function in mitochondria.
J. Biol. Chem. 276(27) , 25262-72, (2001) Reduction of mitochondrial cardiolipin (CL) levels has been postulated to compromise directly the function of several essential enzymes and processes of the mitochondria. There is limited genetic evidence for the critical roles with which CL and its precursor... |
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Modification of a styryl dye binding mode with calf thymus DNA in vesicular medium: from minor groove to intercalative.
J. Phys. Chem. B 116(17) , 5226-33, (2012) This paper reports an interesting transformation of binding mode of 2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide (DASPMI) with calf thymus DNA from minor groove binding in buffer solution to intercalative binding when the dye is encapsulated inside a... |
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Photophysical properties of DASPMI as revealed by spectrally resolved fluorescence decays.
J. Phys. Chem. B 111(26) , 7681-90, (2007) Photophysical properties of 2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide (DASPMI) in various solvents were investigated using time- and space-correlated single photon counting. DASPMI is known to selectively stain mitochondria in living cells.1,2 The... |
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Monitoring sol-to-gel transitions via fluorescence lifetime determination using viscosity sensitive fluorescent probes.
J. Phys. Chem. B 113(35) , 12067-74, (2009) The sol-to-gel transition was monitored via the use of time-resolved recording of the fluorescence emission of viscosity-sensitive probes. Two dyes were chosen for the study, water-soluble DASPMI and a hydrophobic BODIPY, and steady-state, time-resolved and t... |
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How DASPMI reveals mitochondrial membrane potential: fluorescence decay kinetics and steady-state anisotropy in living cells.
Biophys. J. 95(8) , 4068-76, (2008) Spectroscopic responses of the potentiometric probe 2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide (DASPMI) were investigated in living cells by means of a time- and space-correlated single photon counting technique. Spatially resolved fluorescence dec... |
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Neither respiration nor cytochrome c oxidase affects mitochondrial morphology in Saccharomyces cerevisiae.
J. Exp. Biol. 201(Pt 11) , 1729-37, (1998) Previous studies have reported that mitochondrial morphology and volume in yeast cells are linked to cellular respiratory capacity. These studies revealed that mitochondrial morphology in glucose-repressed or anaerobically grown cells, which lack or have redu... |
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Orientational dynamics of a charge transfer complex in cyclodextrin cavity as receptor.
Phys. Chem. Chem. Phys. 10(38) , 5890-7, (2008) This paper reports the structure and dynamics of a twisted intermolecular charge transfer molecule 2-(4-(dimethylamino) styryl)-1-methylpyridinium iodide (o-DASPMI) included inside alpha-, beta- and gamma-cyclodextrin, investigated by using steady state and t... |