Benzimidamide hydrochloride
Benzimidamide hydrochloride structure
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Common Name | Benzimidamide hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1670-14-0 | Molecular Weight | 156.613 | |
| Density | 1.09 g/cm3 | Boiling Point | 332.9ºC at 760 mmHg | |
| Molecular Formula | C7H9ClN2 | Melting Point | 86-88 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 155.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Placental immune response to apple allergen in allergic mothers.
J. Reprod. Immunol. 106 , 100-9, (2014) The immunological milieu in the placenta may be crucial for priming the developing foetal immune system. Early imbalances may promote the establishment of immune-mediated diseases in later life, including allergies. The initial exposure to allergens seems to ... |
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A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis.
PLoS ONE 9(9) , e107182, (2014) Thrombocytopenia is a serious issue connected with the pathogenesis of several human diseases including chronic inflammation, arthritis, Alzheimer's disease, cardiovascular diseases (CVDs) and other oxidative stress-associated pathologies. The indiscriminate ... |
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Intrinsically disordered proteins drive membrane curvature.
Nat. Commun. 6 , 7875, (2015) Assembly of highly curved membrane structures is essential to cellular physiology. The prevailing view has been that proteins with curvature-promoting structural motifs, such as wedge-like amphipathic helices and crescent-shaped BAR domains, are required for ... |
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Ewing's sarcoma of bone tumor cells produces MCSF that stimulates monocyte proliferation in a novel mouse model of Ewing's sarcoma of bone.
Bone 79 , 121-30, (2015) Ewing's sarcoma of bone is a primary childhood malignancy of bone that is treated with X-radiation therapy in combination with surgical excision and chemotherapy. To better study Ewing's sarcoma of bone we developed a novel model of primary Ewing's sarcoma of... |
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Reversible covalent inhibition of eEF-2K by carbonitriles.
ChemBioChem. 15(16) , 2435-42, (2014) eEF-2K is a potential target for treating cancer. However, potent specific inhibitors for this enzyme are lacking. Previously, we identified 2,6-diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile (DFTD) as an inhibitor of eEF-2K. Here we describe its ... |
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Dynamic Redox Regulation of IL-4 Signaling.
PLoS Comput. Biol. 11 , e1004582, (2015) Quantifying the magnitude and dynamics of protein oxidation during cell signaling is technically challenging. Computational modeling provides tractable, quantitative methods to test hypotheses of redox mechanisms that may be simultaneously operative during si... |
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Evaluation of Pseudotrypsin Cleavage Specificity Towards Proteins by MALDI-TOF Mass Spectrometry.
Protein Pept. Lett. 22 , 1123-32, (2015) Trypsin is a protease, which is commonly used for the digestion of protein samples in proteomic experiments. The process of trypsin autolysis is known to produce autolytic peptides as well as active enzyme forms with one or more intra-chain splits. In consequ... |
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Crocin prevents sesamol-induced oxidative stress and apoptosis in human platelets.
J. Thromb. Thrombolysis 38(3) , 321-30, (2014) Recent studies have reported the platelet proapoptotic propensity of plant-derived molecules such as, resveratrol, thymoquinone, andrographolide and gossypol. Meanwhile, there were also reports of phytochemicals such as cinnamtannin B1, which shows antiapopto... |
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Biochemical study and in vitro insect immune suppression by a trypsin-like secreted protease from the nematode Steinernema carpocapsae.
Parasite Immunol. 32(3) , 165-75, (2010) A trypsin-like serine protease was purified by gel filtration and anion-exchange chromatography from the excretory-secretory products of parasitic phase Steinernema carpocapsae. The purified protease exhibited a molecular mass of about 29 kDa by SDS-PAGE and ... |