androsta-1,4-diene-3,17-dione
androsta-1,4-diene-3,17-dione structure
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Common Name | androsta-1,4-diene-3,17-dione | ||
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| CAS Number | 897-06-3 | Molecular Weight | 284.393 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 434.2±45.0 °C at 760 mmHg | |
| Molecular Formula | C19H24O2 | Melting Point | 138-139 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 162.1±25.7 °C | |
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Development of a quantitative method for the simultaneous analysis of the boar taint compounds androstenone, skatole and indole in porcine serum and plasma by means of ultra-high performance liquid chromatography coupled to high resolution mass spectrometry.
Food Chem. 187 , 120-9, (2015) Boar taint is an off-odour occurring while heating meat or fat from boars. A method detecting the three compounds (androstenone, skatole and indole) simultaneously in blood would offer substantial advantages since it would allow monitoring the impact of reari... |
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Cholesterol assimilation and biotransformation by Lactobacillus helveticus.
Biotechnol. Lett. 34(1) , 103-7, (2012) Lactobacillus helveticus, grown at 37°C in MRS medium supplemented with 3 mM cholesterol, assimilated all the cholesterol in 42 h having 68 U mg(-1) of intracellular cholesterol oxidase activity. The strain transformed 1 g cholesterol to 0.05 g of androsta-1,... |
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Evaluation of urinary excretion of androgens conjugated to cysteine in human pregnancy by mass spectrometry.
J. Steroid Biochem. Mol. Biol. 139 , 192-200, (2014) Alterations in the maternal excretion of steroids during pregnancy are not restricted to the production of progesterone and estriol by the fetoplacental unit. Although there is a lack of longitudinal data on urinary androgen concentrations during pregnancy, s... |
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Boldenone, boldione, and milk replacers in the diet of veal calves: the effects of phytosterol content on the urinary excretion of boldenone metabolites.
J. Agric. Food Chem. 55(20) , 8275-83, (2007) Twenty-six veal calves were split into two groups and fed two milk replacers with a different content of phytosterols for 26 days; then, 14 calves (7 animals from each diet) were kept as controls and 12 calves (6 per diet) received daily, per os, a combinatio... |
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Methyl-beta-cyclodextrin alters growth, activity and cell envelope features of sterol-transforming mycobacteria.
Microbiology 153(Pt 6) , 1981-92, (2007) Modified beta-cyclodextrins have been shown previously to enhance sterol conversion to 4-androstene-3,17-dione (AD) and 1,4-androstadiene-3,17-dione (ADD) by growing Mycobacterium spp. The enhancement effect was mainly attributed to steroid solubilization by ... |
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Comparative analysis of genes encoding key steroid core oxidation enzymes in fast-growing Mycobacterium spp. strains
J. Steroid Biochem. Mol. Biol. 138 , 41-53, (2013) Highlights ► Genomes of three strains of mycobacteria producing 3,17-diketoandrostanes from phytosterol were sequenced. ► Genomes of AD and ADD producers are nearly identical, that of 9-OH-AD producer differs. ► Multiple kstD, kshA and kshB genes were found a... |
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Pathology of the testicle and sex accessory glands following the administration of boldenone and boldione as growth promoters in veal calves.
J. Vet. Med. Sci. 69(11) , 1109-16, (2007) Boldenone and its precursor Boldione are illegally used for anabolic purposes in humans, horses and cattle. To develop more effective policies and programs to maximize food security, Italian Public Health Services investigate all indicators capable of assisti... |
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Steroidogenic enzyme gene expression profiles in the testis of cattle treated with illicit growth promoters.
Steroids 76(5) , 508-16, (2011) Recently, the effect of illicit growth promoters (GPs) upon the cattle transcriptome has drawn the increasing attention of the scientific community. In the present study, the pre-transcriptional effects of three different illicit protocols on a set of target ... |
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Bioconversion of 4-androstene-3,17-dione to androst-1,4-diene-3,17-dione by recombinant Bacillus subtilis expressing ksdd gene encoding 3-ketosteroid-Δ1-dehydrogenase from Mycobacterium neoaurum JC-12.
J. Steroid Biochem. Mol. Biol. 135 , 36-42, (2013) The enzyme 3-ketosteroid-Δ(1)-dehydrogenase (KSDD), involved in steroid metabolism, catalyzes the transformation of 4-androstene-3,17-dione (AD) to androst-1,4-diene-3,17-dione (ADD) specifically. Its coding gene was obtained from Mycobacterium neoaurum JC-12... |
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Criteria to distinguish between natural situations and illegal use of boldenone, boldenone esters and boldione in cattle 2. Direct measurement of 17beta-boldenone sulpho-conjugate in calf urine by liquid chromatography--high resolution and tandem mass spectrometry.
Steroids 74(10-11) , 803-8, (2009) Boldenone is banned in the European Union (Directive 96/22/EC) as growth promoter for meat producing animals. Boldione (ADD), boldenone and boldenone esters (mainly the undecylenate form) are commercially available as anabolic preparations, either to the dest... |